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Single Cell Multiome ATAC + Gene Expression

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Unify the transcriptome and epigenome in every cell. Simultaneously profile gene expression and open chromatin from the same cell with Chromium Single Cell Multiome ATAC + Gene Expression. Multiply your power of discovery to characterize cell types and states, and uncover gene regulatory programs.

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One cell, two readouts

Simultaneous detection of mRNA and chromatin accessibility from the same cell.

Define gene regulation

Discover new gene regulatory interactions.

Single cell resolution

Detect rare cell populations with single cell precision.

Flexible and scalable

Profile hundreds to tens of thousands of cells per sample.

Streamlined data analysis

Explore gene expression and chromatin accessibility simultaneously with easy-to-use software.

Efficient lab workflow

From sample to sequencing-ready library in two days.

Multiomic profiling of the transcriptome and epigenome at single cell resolution can transform your understanding of biology. Enhance your characterization of cell types and states, and gain deeper insights into underlying gene regulatory mechanisms with two readouts from every cell. Get started with Single Cell Multiome ATAC + Gene Expression and multiply your power of discovery.
Deeper characterization of cell types and states

Characterize complex cell populations and capture cellular heterogeneity to uncover hidden insights with combined epigenomic and gene expression profiling. Leverage gene expression markers to more easily interpret epigenetic profiles.

Discover new gene regulatory interactions

Combine discovery of regulatory elements with gene expression to explore gene regulatory interactions driving cell differentiation, development, and disease.

Make the most of your precious samples

Maximize insights from your limited samples by obtaining transcriptome and open chromatin information from the same cell.

Explore disease complexity

Understand how gene regulatory networks are disrupted in disease. Interrogate epigenetic remodeling and mechanisms of therapeutic resistance.