S.NEST - Microbioreactor for Cell Line Development
From Bioreactors
Accelerate your cell line development workflow with our revolutionary cell culture technology. As the biopharmaceutical industry expands, companies are looking for competitive advantages in cell line development. The S.NEST, a high-throughput microbioreactor with CO2 incubator functions, shortens the process time for cell upscaling, provides a better microscale environment for cell growth, and brings more efficiency to cell line selection.
-
Most popular related searches
How the S.NEST Works
- Culture: High-throughput cultivation that enables the incubation of four 24-well or 96-well plates at once.
- Optimize: Customizable mixing levels thanks to a unique fluid control system that increases cell growth.
- Improve: Innovative components and thoughtful design which minimizes the impact of evaporation.
- Monitor: Real-time monitoring of pH and dissolved oxygen (DO) values during entire cell culture time line
- Analyze: Intuitive software analysis that transforms data to insights
- Trust: Reliable results allowing you to improve your cell culture workflow
Maximum Productivity With Minimum Effort
The S.NEST introduces suspension culture and late-stage bioreactor conditions to the early-stage cell line development pipeline, providing more growing space and oxygen than static cultures. When using the S.NEST, cells show higher density and viability compared to normal incubation, and weeks of cell expansion are no longer necessary.
The upper section has four incubation chambers, and each includes a thermal module, water tray and air/CO2 inlet pore and sensor. Each chamber also has individual environmental controls and can fit one 96- or 24-well culture plate, enabling the cell culturing of as many as 384 wells at onc
The S.NEST lid comes with 96 or 24 fluidic channels format, covering the corresponding well plates. The patented condenser design in the fluidic channels effectively reduces liquid evaporation. The condensation collected at the surface of condenser circulate back to the culture every mixing.
The lower section is a motion camera module that detects the optical signals from the sensors of each plate within 5 minutes and displays real-time monitoring data on the S.NEST software.
Optical sensors are attached to the bottom of each well to monitor the pH and DO value of all wells simultaneously.
The S.NEST exerts suction or expulsion pressure through the fluidic channels to enable homogenous reciprocating mixing. Adjustable mixing control minimizes shear rate for different cell lines.
The oxygen transfer tubes connecting to the lid offer the cells a continuous oxygen supply to maintain a healthy environment.
Applications
- Cell Line Development
- High-throughput Suspension Culture
- Cell Culture Upscaling
Featured Workflow
Combined with single-cell dispensers such as UP.SIGHT™, laboratories can save up to 13 weeks of processing time.
Customer reviews
No reviews were found for S.NEST - Microbioreactor for Cell Line Development. Be the first to review!