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Boston Pharmaceuticals
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  5. Boston - Model BOS-572 - Spectrum ...

Boston - Model BOS-572 - Spectrum Serine Beta-Lactamase Inhibitor (BLI)

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BOS-572 is a broad-spectrum serine beta-lactamase inhibitor (BLI) of the diazabicyclooctane (DBO) class.

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  • BOS-572 is capable of restoring the antibacterial activity of beta lactams, including piperacillin, against Gram-negative bacteria expressing extended spectrum, AmpC, and serine carbapenemase enzymes.
  • Unlike other DBO BLIs, BOS-572 does not inhibit PBP-2 and lacks measurable antibacterial activity thus simplifying dose-determination of a beta-lactam partner and reducing the potential for the development of resistance.