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ExcellGene - Stabilized Beta Trimeric Spike Protein
FromExcellGene SA
The beta variant — initially found in South Africa — showed additional mutations in the spike protein, the most important ones as K417N, E484K and N501Y (the last one was found already in the Beta variant). Also, the early mentioned D614G mutation remained in this variant.
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- Sequence modifications C-terminal Transmembrane region replaced with a trimerization domain and a polyhistidine tag. Two stabilizing proline mutations. Scrambled S1/S2 furin cleavage site. D614G amino acid change.
- Isolate (Seq ID) 20H/501.V2
- Expression system CHOExpressTMcells
- Purity > 95 % as determined by SDS-PAGE.
- Buffer 0.01M PBS, pH 7.4, no preservatives
- Availability mg to grams