ExcellGene - Model SARS-CoV-2 - Stabilized Delta Trimeric Spike Protein for Delta Variant
The Delta variant of SARS-CoV-2 was first detected in India and has, by November 2021, spread to over 179 countries. It contains again the 614G mutations and others, notably a proline to arginine substitution that may facilitate the cleavage of the S precursor into the S1/S2 conversion, which results in the fusion of the spike protein with the cell membrane receptor ACE2.
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Products Details
- Sequence modifications C-terminal Transmembrane region replaced with a trimerization domain and a polyhistidine tag. Two stabilizing proline mutations. Scrambled S1/S2 furin cleavage site. D614G amino acid change.
- Isolate (Seq ID) 20A/S:478K
- Expression system CHOExpressTMcells
- Purity > 95 % as determined by SDS-PAGE.
- Buffer 0.01M PBS, pH 7.4, no preservatives
- Availability mg to grams
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