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Brainbox - Model NeuroFUS PRO - System for Transcranial Focused Ultrasound Neuromodulation (TUS/tFUS)
The NeuroFUS PRO system for transcranial focused ultrasound neuromodulation (TUS/tFUS) offers unprecedented spatial resolution and adjustable focus, allowing for unparalleled depth of non-invasive transcranial brain or transdermal nerve modulation versus other methods of non-invasive brain stimulation.
ACCOMPANYING SOFTWARE DEVELOPMENT KIT
The NeuroFUS PRO`s Software Development Kit (SDK) provides users with the option to choose from a number of preset, approved neuromodulation pulse sequences contributed by TUS researchers around the world.
TOTAL SAFETY AND COMFORT OF OPERATION
The NeuroFUS PRO comes complete with a range of peripheral safety equipment for ultimate peace of mind and safety during your TUS research, including:
- RFWattmeter monitoring, with inbuilt automatic system shutdown capabilities
- Floating ground transducer casing, hi-pot tested to pass 2MOPP
- Peak and average power limiting systems
- An ergonomic system handle, and a solid water-free coupling bolus to reduce strain on the operator
TRANSDUCER POWER OUTPUT ELECTRONICS
The NeuroFUS PRO is powered by Sonic Concepts, Inc.’s Transducer Power Output drive electronics, commander USB interface and focused annular array transducer technology, and each system is provided fully calibrated with the relevant Certificate of Conformance.
FULL TRAINING & SUPPORT
Each NeuroFUS PRO order is supplemented with an inclusive workshop registration, training sessions, and neuromodulation research consultation.
The NeuroFUS PRO system is a complete, laboratory-ready system that can be used to administer low-intenstity, pulsed transcranial ultrasound stimulation (TUS/tFUS/FUS) to the brain.
What is Transcranial Focused Ultrasound Stimulation?
Transcranial focused ultrasound stimulation (sometimes referred to as transcranial focused ultrasound neuromodulation) is a non-invasive means of brain stimulation that uses low-intensity sound waves (ultrasound) to temporarily affect or alter brain activity in a subject.
TUS offers unprecedented spatial resolution and depth of focus versus other methods of non-invasive brain stimulation - such as TMS, tES, or DBS - and has been shown to be a safe and effective method of delivering precise ultrasonic energy to the brain to without causing tissue damage or lasting neurological effects.
Read a full introduction to transcranial focused ultrasound stimulation here.
What can NeuroFUS offer my research?
The NeuroFUS PRO delivers transcranial (tFUS/TUS) or peripheral focused ultrasound (pFUS) waveforms for the modulation of neuronal activity at a high resolution. Transcranial focused ultrasound stimulation works in a similar way to transcranial magnetic stimulation (TMS), but uses low-intensity pulsed ultrasound (LIFU) in place of magnetic pulses. As a result, NeuroFUS offers significantly higher spatial resolution and is capable of reaching deeper brain regions vs other methods of non-invasive brain stimulation.
Ultimate Flexibility in Study Design
The NeuroFUS PRO system is electromagnetically and mechanically compatible with an extensive range of modern neuroscience research methods and neurotechnologies, including:
- Human behaviour;
- Optical imaging (including techniques such as fNIRS);
- Electroencephalography (EEG);
- Augmented Reality and/or Virtual Reality immersion/stimulation;
- Peripheral nerve stimulation (including Vagus Nerve Stimulation (VNS));
- Brain-computer interfaces (BCIs);
- Computational modelling techniques;
- and other traditional neuromodulation methods such as tES, tDCS, tACS, and TMS.
NeuroFUS` integration with a wide range of complimentary technologies offers researchers the possibility of carrying out truly advanced multimodal neuroscience projects.
The NeuroFUS is intended as a TUS/FUS research system and has not yet been certified as a medical device.
What is Transcranial Focused Ultrasound Neuromodulation?
Transcranial focused ultrasound is an innovative new form of neuromodulation that uses low-intensity sound waves to temporarily affect or alter brain activity.
TUS offers unprecedented spatial resolution and depth of focus versus other methods of non-invasive brain stimulation (such as TMS, tES, or DBS), and has been shown to be a safe and effective method of delivering precise ultrasonic energy to the brain without causing tissue damage or lasting neurological effects.
An Introduction to Transcranial Ultrasound Stimulation:
Dr Lennart Verhagen (Donders Institute) provides an introduction to TUS research techniques in this Brainbox Initiative webinar.
