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Benevolent - The Benevolent Platform
The Benevolent Platform™ is our powerful computational R&D platform. At its core sits our Knowledge Graph, which captures the interconnectivity of all relevant available data and scientific literature. Our suite of exploratory and predictive AI tools allow scientists to interrogate the data and disease networks within the graph, ask biological questions, surface novel insights and triage hypotheses. This allows scientists to visualise the key differentiators between health and disease and pinpoint dysregulated pathways and mechanisms enabling them to identify optimal treatment interventions.
Our Knowledge Graph serves as a data engine for our end-to-end platform and drug discovery programmes. It is built on the foundations of all publicly available biomedical data mined from structured sources, information extracted from scientific literature and internally generated experimental findings.
The Knowledge Graph is constantly enriched and supplies a complete and unbiased representation of biomedical data. Our exploratory tools and predictive models empower scientists to explore relationships in the graph between biological entities and disease networks.
We leverage data at scale, using machine learning models to predict and validate the most biologically relevant, progressible target hypotheses.
Our platform focuses on mechanistic-based drug discovery and combines our knowledge foundations, rapid experimentation, and feedback loops from our in-house labs to improve the quality of our target predictions.
Our machine learning infrastructure powers large scale predictions for disease targets, and provides the evidence behind predicted targets from multiple and disparate data sources, enabling data-driven decisions in target triage.
Diseases are commonly defined by symptoms or location in the body, not by their underlying patient-specific molecular mechanisms or pathways. We leverage multimodal patient-level data to enable data-driven and endotype-specific drug discovery to inform our personalised target identification process.
Our precision medicine workflows empower drug discoverers to identify patient subgroups that could respond similarly to a particular treatment to inform the design of clinical trials.
The space for chemical exploration is infinitely vast, but only a fraction of it can potentially be made into medicines. In chemistry, we combine automation, predictive modelling - including feedback loops from our in-house labs - and structure-based drug discovery methods.
Our AI tools are designed to empower chemists to reach high-quality clinical candidates in fewer iterations, to score and rapidly triage millions of generated compounds following complex molecular profiles defined by drug discoverers, and design better drugs in fewer cycles.