Viridisol - Model M - The Fastest-Growing Solvent in The Pharma Industry

Viridisol® M (2-MeTHF) is a bio-based solvent that is recognized as the most favorable of ether solvents.  The relatively high boiling point (80°C) and low melting point (-137°C) provide a broad temperature range for a myriad of processing conditions. Viridisol® M has a favorable azeotrope with water providing easy options for recycling due to its low (4%) water solubility. This also eliminates the need for an extraction solvent during process work up, as Viridisol® M separates cleanly from water, allowing for easy recovery to an anhydrous form for recycle, all of which minimizes production costs and reduces waste. Viridisol® M has an enhanced stability in the presence of a strong base such as organolithium and is known to stabilize organometallic reagents in hydrocarbon solvents. Toxicity studies have demonstrated Viridisol® M (2-MeTHF) to possess low genotoxicity.