Enterome
Enterome - Model OncoMimics - Therapeutic Cancer Vaccines
FromEnterome
OncoMimicsTM vaccines are a specific combination of bacterial peptides, derived from bacteria present in the gut microbiome, that closely mimic either overexpressed tumor-associated antigens (TAAs) or lineage-specific markers in solid and liquid tumors, respectively.
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- Expected faster, stronger and durable immune responses
- Enterome uses non-self bacterial peptides to target tumors which allow us to tap into a pool of memory T cells with pre-existing immune response
- Excellent immunogenicity
- Enterome uses the highest possible affinity binding peptides (<10nM) derived from our extensive bacterial protein database
- Ability to counteract tumor heterogenicity
- Enterome uses multiple high-affinity peptides in each product targeting multiple key TAAs
- Expected good safety profile
- Tumor expression drives OncoMimics selection
- Potential to access broad patient populations (off-the-shelf)
- De-risked Chemistry, Manufacturing and Control (CMC) and regulatory paths