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Camurus FluidCrystal - Topical Bioadhesive Technology
FluidCrystal topical bioadhesive is a liquid product that forms a bioadhesive film when applied to body tissues. The film acts as an invisible patch, slowly and accurately releasing the active ingredient for the treatment, systemically or locally. It also acts as a protective barrier for sensitive and inflamed tissues. The bioadhesive formulation is suitable for the prolonged local release of active ingredients on the skin and on the mucous membranes of for example the mouth, nose, and throat.
The formulation is applied topically as a low-viscosity liquid. It then spreads, absorbing minute amounts of water and transforming into a thin bioadhesive liquid crystalline film. FluidCrystal® topical bioadhesive products can be administered using metered dose pumps, tubes, and other primary packaging forms for liquids.
The commercially available product episil® is based on the FluidCrystal® topical bioadhesive technology.
- Strong adhesion and retention at biological surfaces
- Protects sensitive tissue
- Relieves topical pain
- High solubilizing capacity for active ingredients
- Extended local or systemic release of pharmaceutical substances
- Good local tolerability
- Manufacturing by standard processes