- Home
- Companies
- BioConnection
- Services
- Commercial Fill and Finish Services
Commercial Fill and Finish Services
BioConnection offers commercial fill and finish for your products. Our capabilities include liquid fill or lyophilization intended for vials, prefilled syringes or blowfill seals. Our large scale state-of-the-art fill and finish line enables you to scale up to commercial production in time for the market.
The large scale filling line has an annual production capacity of up to 40 million vials for liquid products and up to four million vials for freeze-dried products. It features a fully automated filling line (by Groninger, Germany) coupled to a fully automated 10 m2 freeze dryer (by HOF, Germany). This production line is built to meet the highest quality requirements in the (bio) pharmaceutical industry which enabled BioConnection to have the line validated as per the EMA and US-FDA quality guidelines.
With our offer in both clinical scale and commercial scale fill and finish, BioConnection is able to service its clients from four different production lines within one facility in production scales ranging from 0,1L to 1,000L per batch.
- Batch sizes: from 1 unit up to 161,000 units per batch
- Clinical and commercial scale
- Automated fill and hand fill
- Aseptic filling
- Vials: from 2 RDIN up to 50 RDIN
- Syringes: from 0.5 ml up to 10 ml
- Other primary packs: via handfill
- Terminal sterilization
- Formulation development
- Process and analytical development & validation
- Lyo-cycle development and/or optimization
- Transfer and scale-up to clinic
- Transfer and scale-up to market
- Shelf areas ranging from 3 m² up to 10 m²
- Labeling
- Clinical trial packaging
- QP release
- Storage
- Batch sizes: from 1 unit up to 150,000 units per batch
- Clinical and commercial scale
- Automated fill and hand fill
- Aseptic filling
- Vials: from 2 RDIN up to 50 RDIN
- Syringes: from 0.5 ml up to 10 ml
- Other primary packs: via handfill
- Terminal sterilization