Efficacy Testing/Proof-of-Concept

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A core expertise at bioskin is development of innovative test models for evaluation of efficacy of topical drugs and medical devices. In these models biophysical measurement methods can often be used to deliver objective data to support traditional clinical endpoints.  We customize designs for efficacy trials depending on the indication and product profile.
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Established models:
  • Psoriasis plaque test (for anti-psoriatics, also for screening of generic formulations)
  • UV-induced erythema model (for anti-inflammatories)
  • Pain model (for topical analgesics, anti-inflammatories)
  • Vasoconstrictor assay (for corticosteroids)
  • Superficial wound healing (abrasion model, suction blister model for re-epithelization)
  • Expanded flora test (for anti-bacterials)
POC designs:
  • Acne
  • Alopecia/hair growth
  • Atopic dermatitis/eczema
  • Herpes labialis
  • Hypertrophic scars
  • Onychomychosis
  • Psoriasis
  • Tinea pedis
  • Warts