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Thermo Fisher Scientific -Efficient Molecular Testing Solution for COVID-19

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The Thermo Fisher Scientific Amplitude Solution is a new, high throughput, highly automated molecular testing solution that can analyze up to 8,000 COVID-19 specimens in 24 hours. The Amplitude Solution can help laboratories quickly scale COVID-19 testing to volumes needed to help reduce the spread of disease and restore economies and communities. This solution offers maximum throughput with minimal hands-on time, equipment, and staffing.

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Step 3: Sample analysis

  • End-to-end sample tracking and data management within the Amplitude Solution
  • The qPCR run data is automatically analyzed and the COVID-19 test results are generated
  • COVID-19 test results are available to be submitted to your laboratory`s LIMS
  • 1 source for secured assay supply
  • 4-employee operation
  • 1,000 to 8,000 test results per day
  • 24/7 priority support*

As the world leader in serving science, Thermo Fisher Scientific has brought together industry-leading products into a high-throughput, highly automated testing solution with the peace of mind of a secured supply of assays and consumables directly from a single supplier. Your initial purchase comes with an up-front monthly delivery of reagents for your laboratory’s needs over the first year. We will be your partner throughout the process to help ensure your laboratory`s success—from on-site planning, to installation and training, to on-going service and support.

Step 1: Sample transfer and plate prep

Module 1

  • Each sample tube is uncapped, inactivated, and barcoded
  • The tube rack is placed into the Tecan Fluent™ 1080 liquid handler where a negative control, beads/binding solution, proteinase K, and MS2 are added
  • Four 96-deep-well plates are prepared for transfer to the next step

Step 2: RNA extraction and qPCR

Module 2

  • Extracts and purifies RNA from samples
  • Combines 4 x 96-well RNA plates into 384-well reaction plates
  • Performs real-time PCR workflow
  • Separates liquid and plastic waste for easy disposal

At the core of the Amplitude Solution is the Applied Biosystems TaqPath COVID-19 HT Kit, which consistently delivers superior sensitivity and specificity to the SARS-CoV-2 virus. Features include:

  • 20,000 reaction kit to maximize specimen throughput
  • Multi-target design to compensate for emerging SARS-CoV-2 variants and mutations
  • Can signal the presence of the S gene 69-70del mutation and, potentially, B.1.1.7 (501Y.V1 or UK variant)
  • Sensitive and specific assay to help increase confidence in results

Trusted priority service partnership
Our service team will be your laboratory`s single point of contact, handling installation, system qualification, and staff training to ensure your lab is quickly operating at its peak.

Get answers and keep moving
We offer a rapid response 24/7, 365 days a year for both in-person and remote troubleshooting depending on your specific needs.* Our service partnership includes planned maintenance visits to solve problems before they arise and on-hand locally stocked parts for those unavoidable repairs to minimize downtime and keep your lab moving forward.