Genome Annotation Services
From Bioinformatics Service Provider & Consultancy - Bioinformatics Consultancy Services
How Our Genome Annotation Services Can Help You ? RASA Bioinformatic Lab’s genome annotation services provides you a closer view on the genomic data analysis in understanding the data along with mapping, annotation and as well as comparative genome analysis of two different strains of same species, understanding its working de novo assembly of the genomic data and furthermore providing de-novo based RNA-Sequence Analysis of the data obtained. The impact of NGS technologies on genomics is far reaching and likely to change the field for years to come.
Services Overview
NGS technologies have demonstrated the capacity to sequence DNA at unprecedented speed, thereby enabling previously unimaginable scientific achievements and novel biological applications. Among which, genome annotation has remarkably gained the NGS applications, hence providing a huge area for genome annotation services for bioinformatics companies worldwide. But, the massive data produced by NGS also presents a significant challenge for data storage, analyses, and management solutions. RASA Bioinformatic CRO Lab’s genome annotation services use advanced bioinformatics tools which are essential for the successful application of NGS technology. This results in striking impact on genomic research and the entire biological field including mapping, genome annotation and functional predictions along with comparative genomics analysis. Rasa Bioinformatic Lab’s genome annotation services also enlighten the path towards its ability in tackling the unsolved challenges unconquered by previous genomic technologies.
Key Areas of Genome Annotation services
De-Novo Assembly
De novo assembly or sequencing refers to sequencing a novel genome where there is no reference sequence available for alignment. Sequence reads are assembled as contigs, and the coverage quality of de novo sequence data depends on the size and continuity of the contigs (ie, the number of gaps in the data). Next-generation sequencing (NGS) enables faster, more accurate characterization of any species compared to traditional methods, such as Sanger sequencing. Hence, genome assembly refers to the process of taking a large number of short DNA sequences and putting them back together to create a representation of the original chromosomes from which the DNA originated. Wherein, de novo genome assemblies assume no prior knowledge of the source DNA sequence length, layout or composition. In a genome sequencing project, the DNA of the target organism is broken up into millions of small pieces and read on a sequencing machine. These “reads” vary from 20 to 1000 nucleotide base pairs (bp) in length depending on the sequencing method used. RASA Bioinformatic Lab’s genome annotation services can provide you a closer view on the de novo assembly and genome data analysis and furthermore providing de-novo based RNA-Sequence Data Analysis services for the obtained data.
Gene Mapping Service
Among the main goals of the Human Genome Project (HGP) was to develop new, better and cheaper tools to identify new genes and to understand their function. One of these tools is gene mapping. Genemapping also called linkage mapping can offer firm evidence that a disease transmitted from parent to child is linked to one or more genes. Gene Mapping also provides clues about which chromosome contains the gene and precisely where the gene lies on that chromosome.
Genetic maps are also useful in guiding scientists to the many genes that are believed to play a role in the development of more common disorders such as asthma, heart disease, diabetes, cancer, and psychiatric conditions. Identification of genes is usually the first step in understanding a genome of a species; mapping of the gene is usually the first step of identification of the gene. Gene mapping is usually the starting point of many important downstream studies. Hence we at RASA Bioinformatic CRO Lab’s genome annotation services can also perform gene mapping annotation to discover genes responsible for a disease or disorder or just to get data sufficient enough as the genetic counselling requirements, etc.
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