In Vitro Analysis

In vitro analytical tools allow for the study of various critical quality attributes like production yield, target- and/or poly-reactivity, colloidal stability, melting temperature, self- and/or cross-interaction, solubility, and fragmentation. IPA is equipped with a state-of-the-art bio-inert HPLC enabling analytical determination of mAb biochemical and biophysical properties such as aggregation levels (SEC-HPLC), colloidal stability (SMAC-HPLC), cross interaction (CIC-HPLC), Asn deamidation and isomerization (CIEX-HPLC), and Met/Trp oxidation (HIC-HPLC).