Antibodies Discovery Service Services
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Manufactured by MedGenome Inc.based in USA
Antibody discovery is an important component for early-stage research studies, diagnostics, and therapeutics. Hybridoma technology has been the forefront tool in generating monoclonal antibodies but is time consuming and costly. MedGenome’s proprietary HitMab platform now enables researchers to identify antigen-specific ...
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Manufactured by Celemics, Inc.based in SOUTH KOREA
TrueRepertoire. Immune Repertoire ...
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Manufactured by Synbio Technologies LLCbased in USA
The binding affinity of an antibody is one of the key parameters to determine the efficacy and dosage of an antibody drug. Currently, the methods for improving the binding affinity of antibodies mainly focus on site-mutation, CDR rearrangement, DNA recombinant, etc. With our unique and effective affinity maturation technology, we can quickly ...
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Manufactured by Synbio Technologies LLCbased in USA
The immune system is a very robust “antibody factory” that consistently produces antibodies to fight infections and diseases by recognizing and targeting infected cells or pathogens (antigens). The emergence of single B cell antibody technology has enabled a new strategy for discovery of naturally occurring ...
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Manufactured by Synbio Technologies LLCbased in USA
Complex structures and high production costs associated with monoclonal antibodies (mAbs) have limited their achievable clinical applications. For this reason, scientists focusing on antibody drug discovery have shifted their interests toward recombinant antibody ...
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Manufactured by Synbio Technologies LLCbased in USA
Accurately acquiring antibody sequences is one of the most important prerequisites to achieving antibody functional optimization and expression of recombinant engineering antibodies. Antibody sequencing and analysis also plays a key role for researchers publishing articles and apply for patents. The data is even more critical for ...
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Manufactured by Synbio Technologies LLCbased in USA
class of pharmaceuticals generated by using principles and methods of biology, immunology, physical chemistry, and pharmacology, etc. These drugs utilize the composition of various organisms and biological tissues, as well as organs. Biological drugs usually include genetic engineering drugs, antibody engineering drugs, blood products ...
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Manufactured by Synbio Technologies LLCbased in USA
Hybridoma technology features the effective usage of innate functions of both immune and cancer cells to generate monoclonal antibodies (mAbs). The resulting hybridoma cell lines are produced to combat specific antigens of interest. Such technology has forged remarkable new approaches toward therapeutic mAb discovery, as well as disease ...
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Manufactured by Synbio Technologies LLCbased in USA
Obtaining the hybridoma monoclonal antibody (mAb) sequence is one of the key requirements of recombinant antibody engineering. Synbio Technologies provides both accurate and efficient monoclonal antibody sequencing services. To accomplish this, we utilize special primer sets and advanced sequencing techniques to help our ...
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Manufactured by Synbio Technologies LLCbased in USA
Immune Repertoire refers to the set of all functionally diversified B cells and T cells in the circulatory system of an individual at any given time. Immune repertoire sequencing (Immuno-Seq) targets at T/B lymphocytes and utilizes the 5’ Rapid Amplification of cDNA Ends (RACE) Technology. The 5’ RACE technology amplifies complementarity-determining regions (CDRs) of B cell receptors ...
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Manufactured by Synbio Technologies LLCbased in USA
Immunogenicity or Human Anti-Mouse Antibodies (HAMA) response is what happens when antibodies derived from xenogeneic sources are administered to humans. This can potentially decrease the effectiveness of immune-treatment through rapid clearance of the therapeutic antibody or immune-conjugate. In some cases, the patient may even ...
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