Antigen Presentation Services
10 services found
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
To accelerate the development of cancer immunotherapy, it is essential to systematically identify tumor antigens that are truly tumor-specific, patient-shared, stably expressed (i. e., cloned) and immunogenic in all malignant cells. Immunopeptidomics is a large-scale and in-depth approach capable of identifying and quantifying the presented human leukocyte ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Functionally, cDCs include two states: immature and mature. Immature DCs are professional in uptaking and processing antigens, and mature DCs are specialist in antigen presentation. It has been observed that immature cDCs can induce immune tolerance, while mature cDCs induce Th2 or Th1 immune responses. ...
Manufactured by:PharmAbcine Inc. based inYuseong-gu, SOUTH KOREA
The dual target antibody platform technology of PharmAbcine is based on the fully human antibody candidates selected from HuPhage biopanning process. Depending on antigen presentation patterns on target cell types and the related drug MOA, various bispecific platforms (DIG-body, PIG-body and TIG-body) are adopted in our antibody engineering strategy. Currently, ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Autophagy has an important role in diverse physiological processes such as adaptation to nutrient starvation, cell death, embryonic development, energy metabolism, and antigen presentation, among other events. Moreover, autophagy has been highlighted as a crucial component of pathological processes such as cancer, hypoxia, pathogen infection, and ...
by:Istari Oncology Inc. based inMorrisville, NORTH CAROLINA (USA)
The tumor environment contains all the ingredients needed to mount an anticancer immune response—tumor antigens, antigen presenting cells (APCs, including tumor-associated macrophages [TAMs] and dendritic cells), and T cells—but activation of the immune system to generate that antitumor response is complex and multifaceted. By ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
As the main component of the immune system, T cells protect the body from infections and tumors by a diversity of bio-functions, including recognition and presentation specific antigens, directly killing target cells, secretion cytokines, assisting or inhibiting antibody production by B cells, etc. These functional T cells are distinguished by a variety of ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Tumor immunotherapy utilizes active or passive methods to provoke tumor-specific immune responses in the body, harnessing their inhibitory and cytotoxic functions against tumor cells. Characterized by its specificity, efficacy, and mitigation of collateral damage, immunotherapy distinguishes itself from conventional methods such as surgery, targeted therapy, and ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
T cells play a vital role in destroying pathogens and monitoring pathological cells. They are able to distinguish between self-antigens and non-self-antigens by surface T cell receptors (TCRs). Most human T cells express the classical TCRs, which consists of TCRα and TCRβ chains co-expressed with CD3 chains (γ, δ, ε, and ζ). ...
Manufactured by:Greenwich LifeSciences, Inc. based inHouston, TEXAS (USA)
Cancer Immunotherapies are a New Method of Cancer Treatment. Among the more established treatment options, such as surgery, chemotherapy, targeted therapy, and radiation therapy, cancer immunotherapy is a rapidly emerging and important field. It has led to new clinical research studies and has garnered the attention of biotechnology and pharmaceutical companies, regulatory agencies, payors and ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Nanoparticles (NPs) undergo interactions with serum proteins during systemic administration, which may result in the formation of protein corona (PC). Investigating the interplay between the chemical and biological properties of NPs enhances clinical translation efficiency. NPs with PC can be considered to exhibit a distinct biological ...