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Bioinformatics Research Services
53 services found
by:Creative Proteomics based inNew York, NEW YORK (USA)
KEGG, abbreviation of Kyoto Encyclopedia of Genes and Genomes, is a collection of databases, which is used for bioinformatics research, including data mining in genomics, proteomics, metabolomics and other omics studies, modeling and simulation in systems biology, and translational research in drug R & ...
Manufactured by:Epigentek Group Inc. based inFarmingdale, NEW YORK (USA)
Targeted Bisulfite Sequencing is an NGS method used to evaluate site-specific DNA methylation changes. The process is similar to pyrosequencing but offers a much higher throughput overall. Our next-generation sequencing platforms can deliver a great amount of useful DNA methylation information with publication-ready data parsed by our expert bioinformatics scientists. The methylation analysis at ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Glycosylation modification not only affects the spatial conformation, biological activity, transport, and localization of proteins, but also plays a crucial role in specific biological processes such as molecular recognition, cell communication, and signal ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
To assess the appropriateness of candidate metabolites and to more comprehensively and intuitively display the relationships among samples and the differential expression patterns of metabolites across different samples, hierarchical clustering is utilized based on the expression levels of significantly differential metabolites. This approach aids in accurately identifying marker metabolites and ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Cholesteryl esters derived from cholesterol, are dietary lipids. They form when enzymes in the human body metabolize cholesterol with an ester bond between the carboxyl group of fatty acids and the hydroxyl group of cholesterol. Cholesteryl esters are extensively found in animal body fluids (plasma lipoproteins) and can also appear as fatty streaks in blood vessel walls, contributing to ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
High-throughput methods in metabolomics research generate extensive data on metabolite analysis, requiring bioinformatics methods for processing. Bioinformatics analysts at BGI (Beijing Genomics Institute) can deeply explore and comprehensively analyze metabolomics data from raw mass spectrometry data by performing peak alignment, retention time ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
MtoZ Biolabs offers meat biomarkers analysis service using UPLC/TripleQuad5500, with high accuracy, specificity, and sensitivity. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Structure-activity relationship (SAR) technology plays an increasingly important role in dealing with large and ever-expanding data sources. SAR techniques are widely used, including: the computational simulation design of virtual chemical libraries to explore molecular diversity for subsequent synthesis and screening; screening proprietary, commercial, and public databases to discover lead ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Gangliosides are a large class of complex lipids that are abundant in the neuronal cell membranes in the brain. These molecules consist of sphingolipids with one or more sialic acids attached to the sugar chain. As structural components of cell membranes, gangliosides have their two hydrocarbon chains embedded in the plasma membrane, while the oligosaccharides are located on the cell surface, ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
MtoZ Biolabs provides bile acids analysis service using UPLC/TripleQuad5500, which can quantitatively analyze over 90 kinds of bile ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Glycosphingolipids are widely present in cell membranes and serum. They either exist in free form or are complexed with other proteins. The glycan head group determines the biological function of glycosphingolipids. Abnormal glycosylation of glycosphingolipids is closely related to various cancers, such as breast cancer, lung cancer, and brain tumors. Glycosphingolipid glycans are also involved ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Polyprenols are long-chain isoprenoid alcohols. The general formula for polyprenols is H-(C5H8)n-OH, where n refers to the number of isoprene units. Polyprenols are classified into three types: all-trans (solanesol-type), two-trans (Solanesol-type) and poly-cis (Betulaprenol-type), and three-trans and poly-cis (Ficaprenol-type). Despite their low content, polyprenols are natural bioregulators ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Polyunsaturated fatty acids (PUFAs) are primarily classified into ω-3 and ω-6 fatty acids. The difference between these two fatty acids lies in the position of the first double bond from the methyl end of the fatty acid chain. ω-6 fatty acids have a carbon-carbon double bond at the n-6 ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Lipids, small molecules that are either hydrophobic or amphipathic, include fats, waxes, sterols, and fat-soluble vitamins (A, D, E, and K), monoacylglycerides, diacylglycerides, and phospholipids. In biological physiology, lipids play crucial roles not only in energy storage and structural components of cellular membranes but also in facilitating signal transduction, membrane transporting, and ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
KEGG (Kyoto Encyclopedia of Genes and Genomes) database is a database used for systematic analysis of metabolic pathways and functions of gene products in cells. KEGG helps to study genes and its expression information as a whole network. KEGG integrates data from genomes, chemical molecules, and biochemical systems, including metabolic pathways (PATHWAY), drugs (DRUG), diseases (DISEASE), gene ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Far-western blot is a molecular biology method based on western blot technology that can be used to detect protein-protein interactions in vitro, especially interactions that do not require the natural structure of the target ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Leukotrienes (LTs) are a group of inflammatory lipid mediators derived from arachidonic acid (AA) via the 5-lipoxygenase (5-LOX) pathway. A characteristic feature of LTs is that they are produced by leukocytes and share a conjugated triene structure. LTs consist of cysteinylleukotrienes (CysLTs) and leukotriene B4 (LTB4). CysLTs contain a cysteine ring, whereas LTB4 is a noncysteine containing ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Carbon metabolism analysis in MtoZ Biolabs encompasses both one carbon metabolism and central carbon metabolism. The metabolism of certain amino acids can produce groups containing a carbon, known as one carbon unit (C1 unit). These groups can participate in biosynthesis upon transfer. The metabolic processes involving the production and transfer of C1 unit are referred to as one carbon ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Sphingolipids are fundamental structural components of cell membranes, forming lipid rafts by combining with other components. Sphingolipids are involved in regulating biological processes such as cell growth, differentiation, and apoptosis. Ceramide is the central hub of the sphingolipid pathway, including sphingomyelin, glucosylceramide, and galactosylceramide, and is mainly divided into ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
During the production of bioproducts, it's common to find impurities not only produced in the manufacturing process but also related to the desired products. These product-related impurities typically consist of product variants that do not align functionally with the target product. The most common variants arise from chemical modifications, as well as from the degradation and aggregation of the ...