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Blood Brain Services
17 services found
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Pericytes are vascular mural cells embedded in the basement membrane of blood microvessels. They extend their processes along capillaries, pre-capillary arterioles and post-capillary venules. Pericytes regulate blood-brain barrier (BBB) permeability, angiogenesis, clearance, cerebral blood flow (CBF), neuroinflammation and stem ...
by:EnClear Therapies based inNewburypor, MASSACHUSETTS (USA)
Localized CNS delivery of therapeutics & monitoring of CSF to ensure effective & personalized ...
by:SonALAsense based inBerkeley, CALIFORNIA (USA)
Glioblastoma multiforme (GBM) patients face a dismal prognosis, with recurrence virtually inevitable. RGBM has no currently effective means of ...
Manufactured by:BrainCool AB based inLund, SWEDEN
A stroke happens when blood supply to the brain is interrupted or reduced, either by a blockage (ischemic stroke) or a blood vessel rupture (hemorrhagic stroke). This leads to rapid cell death due to oxygen and nutrient deprivation, causing various symptoms and complications depending on the affected brain area. Quick treatment ...
Manufactured by:MODAG GmbH based inWendelsheim, GERMANY
Certain proteins including α-synuclein can form disease-specific fibrillar amyloid aggregates. The misfolding/ aggregation pathway resulting in amyloid fibrils involves characteristic oligomer species which have been shown to be the most relevant toxic protein species. These pathological oligomers exhibit structural epitopes that are not found in physiologically folded proteins or ...
by:Lena Biosciences, Inc. based inAtlanta, GEORGIA (US) (USA)
We routinely run assays with primary cells and iPSC-derived cells. Organ models: liver, brain, blood and tumors. Normal tissue models: 3D cell-based culture and co-culture models. Tumors: lung, breast, liver etc. We can test small molecules and biologics with tissue slices, and organoids, and maintain cell diversity in the unaltered patient tissue. ...
Manufactured by:NeoClone based inMadison, WISCONSIN (USA)
NeoClone is fast becoming a leader in the single domain antibody library field. We offer a wide range of unique services, including construction of immunized single domain antibody libraries using our llamas, bio-panning of naïve or immunized single domain antibody libraries and large scale production of single domain antibodies ...
Manufactured by:Pion based inBillerica, MASSACHUSETTS (USA)
Pion Analytical Services offers comprehensive support for drug development activities by providing sophisticated assays, analyses, and interpretations that help in understanding pharmacokinetic parameters at an early stage in the development process. With our advanced instrumentation, in vivo-level insights can be obtained in vitro. Our services include establishing primary characteristics of ...
Manufactured by:Nexelis based inSeattle, WASHINGTON (USA)
Including Pharmacokinetics and Immunogenicity. Designed to be an extension of your laboratory, Nexelis, a Q² Solutions Company, supports bioanalysis in all phases with agile assay development to validation mindset. Whether we design a custom bioanalytical assay or support a client’s technology transfer, our method development process results in an optimized assay compliant with global ...
by:Advancells based inNoida, INDIA
Stroke is mainly characterized by a decreased supply of oxygenated blood to two primary organs of the body, either heart or brain, especially due to blocked and/or ruptured arteries. Specifically, there are three type of Stroke: (a) Ischemic stroke , when the blockage of the oxygenated blood is due to blood clots, and (b) ...
by:Envision Radiology based inColorado Springs, COLORADO (USA)
A computed tomography angiography or CT angiography is a medical test in which a patient will receive an injection of a special dye through an IV in their arm or hand before undergoing a CT scan to produce detailed pictures of blood vessels and tissues. Computerized tomography scans or CT scans are X-rays that create cross-sectional images of your body with a computer. The CT scanner consists of ...
by:Advancells based inNoida, INDIA
“Cerebral” indicates a part of the brain and “Palsy” refers to muscular weakness. Cerebral Palsy is a broad term comprising of several non-progressive “Chronic Palsies” that affect balance, movement, posture, intelligence quotient, and muscle tones. Although the symptomatic expression of Cerebral Palsy may start at any age, the cause of its ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Endocannabinoids are amphipathilic molecules synthesized from phospholipids in the nervous system. They are a part of the endocannabinoid system, which includes G protein-coupled receptors. The most extensively studied endocannabinoids are N-arachidonoylethanolamine (anandamide) and 2-arachidonoylglycerol ...
Manufactured by:Ascendia Pharmaceuticals based inNorth Brunswick, NEW JERSEY (USA)
Parenteral formulation development for drugs delivered by injection or infusion is the fastest and the second most common route of drug administration. These formulations must achieve good compatibility of the drug substances with the excipients and the primary container. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Receptors are biomolecules that can bind with hormones, neurotransmitters, drugs, or intracellular signaling molecules and are capable of inducing changes in cellular function. Receptors are categorized based on their cellular location into cell surface receptors and intracellular receptors. Each receptor typically has two active sites: one that recognizes and binds to the ligand and another ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Nanoparticles (NPs) undergo interactions with serum proteins during systemic administration, which may result in the formation of protein corona (PC). Investigating the interplay between the chemical and biological properties of NPs enhances clinical translation efficiency. NPs with PC can be considered to exhibit a distinct biological ...
Manufactured by:Ascendia Pharmaceuticals based inNorth Brunswick, NEW JERSEY (USA)
Parenteral formulation development for drugs delivered by injection or infusion is the fastest and the second most common route of drug administration. These formulations must achieve good compatibility of the drug substances with the excipients and the primary container. Successful formulation development can determine drug patentability, lifecycle, and overall market success. With growing ...