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Mtoz Biolabs Cell Based Therapy Services
3 services found
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
T cells play a vital role in destroying pathogens and monitoring pathological cells. They are able to distinguish between self-antigens and non-self-antigens by surface T cell receptors (TCRs). Most human T cells express the classical TCRs, which consists of TCRα and TCRβ chains co-expressed with CD3 chains (γ, δ, ε, and ζ). ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
To accelerate the development of cancer immunotherapy, it is essential to systematically identify tumor antigens that are truly tumor-specific, patient-shared, stably expressed (i. e., cloned) and immunogenic in all malignant cells. Immunopeptidomics is a large-scale and in-depth approach capable of identifying and quantifying the presented human leukocyte antigen (HLA) immunopeptidome. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
The immunopeptidome comprises all short peptides presented on the cell surface by HLA-I and II molecules for T-cell recognition. Immunopeptidomics analysis aims to explore the dynamics and composition of both type I and II immune peptides. Comprehensive characterization of the immunopeptidome aids in developing new therapies for cancer, immune diseases, and infectious diseases. ...