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Disease Insect Models Services
37 services found
Manufactured by:Curi Bio based inSeattle, WASHINGTON (USA)
Curi Bio’s iPSC Repositories Available for Services. Custom Panel of Different Gender and Ethnicities. Disease Model Pairs. Patient-derived iPSC-lines. Isogenic DMD/WT Myoblasts. Isogenic DMD/WT ...
by:Oncodesign based inDijon, FRANCE
An extension of our innovation technology platforms, SOLO involves a wide range of distinct and diversified services. It covers an extensive spectrum of pharmaceutical expertise and the ability to design and carry out precise and ad hoc assessments in the discovery and development of new therapies.Drawing on our experience and expertise in the preclinical investigation of new therapeutic entities ...
Manufactured by:TissUse GmbH based inBerlin, GERMANY
TissUse offers high-value service contracts to create custom solutions for safety evaluation of drugs, cosmetics and chemicals, and pre-clinical human disease modelling. Any new chip design serving customer needs with a specific organ arrangement can be prototyped and produced at short notice due to a proprietary rapid prototyping procedure established at TissUse. The versatile TissUse approach ...
Manufactured by:Cytosurge AG based inGlattbrugg, SWITZERLAND
Custom CRISPR cell line engineering service based on our FluidFM® ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Rodent disease models are widely used for a broad range of project objectives, which involve investigation of pathological process and mechanism of disease, pre-clinical tests of potential therapeutic agents, ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Over the past two decades, extensive collections of zebrafish lines carrying mutations in genes involved in early embryonic development have been generated—some of these mutations in genes important for eye formation and associated with eye malformations in humans. Besides, many transgenic lines have been generated at Creative Biogene to enable the close monitoring of organogenesis and the ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
It is indispensable and effective to use animal disease models in experimental medical research. Animal models of neurological disease provide a convenient and reliable platform for developing new therapies and drugs for such diseases. Creative Bioarray uses animal models of different neurological diseases to provide professional drug or therapy testing and research services. ...
Manufactured by:Kiadis Pharma NV based inAmsterdam, NETHERLANDS
Our efforts in haematology are currently focussed on non-malignant blood disorders including forms of anaemia. Our approach is to identify functional and developable lead molecules and quickly proceed to verified animal disease models to study the direct impact of our drug candidates with clinically relevant read outs. We build our know-how by working on common pathways that are frequently used ...
by:Neuron Experts based inMarseille, FRANCE
To keep up its high level of Competitiveness, Neuron Experts constantly develops new cellular models to provide the most accurate answers to customers’ needs: Development of new neurodegenerative disease models following current discoveries of new therapeutic targets, Development of new cellular models to study interaction between neurons and skin, Development of human Induced Pluripotent ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene has long-standing experience in conducting preclinical zebrafish model studies of cardiovascular disease. We offer consultancy and preclinical zebrafish models of cardiovascular disease including hypertension, arrhythmia, heart failure and atherosclerosis, etc. Similar to other animal models, wild-type zebrafish do not spontaneously develop cardiovascular diseases mimicking the ...
Manufactured by:SCIREQ - an emka TECHNOLOGIES Company based inMontreal, QUEBEC (CANADA)
VAAD is a new innovative technique using the flexiVent, introduced to improve in vivo aerosol administrations for drug delivery and disease modelling. The VAAD approach minimizes subject-to-subject variability, and fosters a highly homogenous aerosol deposition within the lung. This optimized aerosol protocol is synced with mechanical ventilation to standardize features of the subject’s ...
Manufactured by:Curi Bio based inSeattle, WASHINGTON (USA)
Curi Bio has a repository of iPSC’s for disease modeling and proprietary technologies for differentiating these cells into myoblasts and cardiomyocytes. Curi has developed in vitro 3D disease models for multiple disease phenotypes. In addition, Curi has the capability of generating new gene-edited iPSC models in ...
Manufactured by:Stem Pharm, Inc based inMadison, WISCONSIN (USA)
Stem Pharm offers a variety of services allowing for custom projects and biomaterials tailored to each customers’ ...
Manufactured by:Cloud-Clone Corp. based inKaty, TEXAS (USA)
The development of human disease is very complex, to itself as experimental object to in-depth study of the mechanism of disease, the accumulation of clinical experience not only in time and space are limited and many experiments on the moral are restricted. Animal models can provides the basic platform for the study of safety research of drugs, biological products, medical polymer materials, ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Genomic engineering in cell lines is a versatile tool for studying gene function, designing diseases models, biopharmaceutical research, drug discovery and many other applications. CRISPR (Clustered Regulatory Interspaced Short Palindromic Repeats)/Cas9 systems is a newly developed yet the most popular method for genome editing. It has been widely used in current biology, functional genome ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
In vivo studies are done toward the end of the lead optimization process on selected candidates for final characterization and selection. GLP studies are done only for development compounds being prepared for clinical trials. Creative Bioarray has conducted in vivo testing for cardiovascular disease using in vivo models for both side-effect profiling and efficacy according to your requirement. ...
Manufactured by:SCIREQ - an emka TECHNOLOGIES Company based inMontreal, QUEBEC (CANADA)
Surgical skills are needed for all our implanted telemetry and for some in vitro isolated organs ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
Capture and understand human disease biology in vitro. The key to unlocking effective therapies for the unsolved diseases of our times is a deep understanding of human disease biology. To this end, MIMETAS aims to capture the essence of diseases in fit-for-purpose in vitro models. We are fully committed to reducing human disease complexity into functional and screenable ...
by:Selvita S.A. based inKrakow, POLAND
Having experience in both pharma and biotech R&D, we are well aware of what it means to discover a hit and transform it into a drug. You can best benefit from this “insider” experience through our integrated drug discovery services built ...
by:elminda Ltd. based inHerzliya, ISRAEL
CNS drugs exhibit the lowest approval success rates due to multiple challenges such as lack of efficacy in early and advanced stages of development, Poor target selection / engagement, poor translation from pre-clinical models and disease heterogeneity. BNA may contribute in CNS research and drug development by adding new objective endpoints, assisting in understanding drug mechanism, identifying ...