Refine by
Disease Progression Services
15 services found
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Humans are highly organized systems comprised of approximately 3.72×1013 cells of various types, which maintain proper organ function and normal cellular homeostasis. Despite significant and revolutionary discoveries in the field of cell biology, the heterogeneity of cells still requires further investigation. Single-cell RNA sequencing (scRNA-seq) has become the latest method for revealing the ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Since urine lacks homeostatic regulation, it can reflect metabolic disturbances, providing insights into systemic changes in response to physiological challenges or disease ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Proteolysis targeting chimera (PROTAC) drugs offer a novel approach to disease treatment by leveraging the body's innate protein degradation pathways. In contrast to traditional small-molecule inhibitors, PROTAC drugs promote the degradation of specific proteins rather than directly inhibiting their function, thus mitigating or eliminating their role in disease ...
by:PIXIUM VISION based inParis, FRANCE
Age-related macular degeneration is the leading cause of severe vision loss and legal blindness in people over the age of 65 in North America and Europe. The global impact is significant with current projected estimates for people living with AMD of around 200 million people worldwide and expected rapid growth due to aging ...
by:Curemark based inRye Brook, NEW YORK (USA)
Parkinson’s disease (PD), a progressive disorder of the nervous system with both motor and non-motor symptoms, currently affects one million people in the United States, with 50,000-60,000 new cases diagnosed each year. Although no cure exists for PD, various medications, surgeries, and physical therapies can help improve symptoms and reduce the ...
Manufactured by:Regeneus Ltd. based inPaddington, AUSTRALIA
Regeneus manufactures MSC’s under strict quality standards. In accordance with the guidelines set by the International Society for Cellular Therapy (ISCT) and our rigorous testing we are easily able to identify MSC donor ...
by:ForeSee Medical, Inc. based inSan Diego, CALIFORNIA (USA)
Medical algorithms are mathematical models used to make decisions in the field of medicine. These algorithms take into account a variety of factors, including patient symptoms, medical history, and test results. They are used to support decision-making in a wide range of areas, including diagnosis, treatment planning, and clinical research. Medical algorithms can be based on statistical methods, ...
Manufactured by:MODAG GmbH based inWendelsheim, GERMANY
Certain proteins including α-synuclein can form disease-specific fibrillar amyloid aggregates. The misfolding/ aggregation pathway resulting in amyloid fibrils involves characteristic oligomer species which have been shown to be the most relevant toxic protein species. These pathological oligomers exhibit structural epitopes that are not found in physiologically folded proteins or ...
Manufactured by:Angany Inc. based inSt-Jean, QUEBEC (CANADA)
A silent pandemic… Allergy is a chronic progressive disease with serious complications evolving over decades of life. Allergy can be viewed as the result of one’s immune response “stalled” in a pre-natal state, with the “normal”, protective type of immune response failing to kick-in. Genetic, environmental and lifestyle ...
Manufactured by:Advanced Cell Diagnostics, Inc. based inNewark, CALIFORNIA (USA)
ACD's Professional Assay Services group has been developing RNAscope™ biomarker assays for our biopharma partners for a decade. Our biomarker assays have contributed to important clinical trial exploratory endpoints, enabled more accurate patient selection, and are leading to CDx development with our partner, Leica Biosystems. Leveraging the unrivalled sensitivity and specificity of ...
Manufactured by:MacuLogix based inMiddletown, PENNSYLVANIA (USA)
Active monitoring of AMD can allow patients to enjoy additional years of good central vision, enhancing the odds of a better quality of life. Diagnosing the disease as early as possible offers time to take measures that may slow ...
Manufactured by:Resoundant, Inc. based inRochester, MINNESOTA (USA)
Resoundant offers Core Lab services in collaboration with the Mayo Clinic scientists and medical professionals who invented MR Elastography over 20 years ago. Today, Resoundant and Mayo Clinic continue to support the ongoing advancement of MRE through joint research and development activities. Resoundant Core Imaging personnel also hold joint appointments in Mayo’s MRE laboratory, and are ...
Manufactured by:Ascendia Pharmaceuticals based inNorth Brunswick, NEW JERSEY (USA)
Biological formulation development involves discovering solutions for the most bioactive, native protein delivery. It poses a myriad of challenges due to the fact biologics consist of generally large, complex molecules that complicate drug development. Biologics are at the forefront of many current medical advances. They have established a key position in the pharmaceutical market by ...
Manufactured by:Bone Therapeutics SA based inMont-St-Guibert, BELGIUM
Bone Therapeutics' products are currently in clinical studies for three indications: Knee osteoarthritis. Fractures at risk of non-healing. Degenerative spine disorders: spinal fusion ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
A key step in drug discovery is target identification—identifying "druggable" biological targets. After a target is identified, it must be validated to demonstrate the functional relationship between the target and disease phenotype while ensuring safety. The drug discovery process is lengthy and costly, but good target validation increases the likelihood of developing effective drugs and ...