Drug Candidate Services
35 services found
by:Solvias AG based inKaiseraugst, SWITZERLAND
Most drug substances are marketed as crystalline material. Having a crystalline drug candidate is beneficial to development processes and simplifies registration. We offer crystallization screening services and also complete crystallization development ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
ADMET stands as an abbreviation for absorption, distribution, metabolism, excretion, and toxicity in pharmacokinetics and pharmacology. These properties describe the reaction of a drug medication within an organism, human, or animal, which helps scientists evaluate their drug candidates and select compounds that are likely to have the desired ...
by:Reaction Biology Corp. based inMalvern, PENNSYLVANIA (USA)
Cell-based assays are valuable to probe new drug candidates in the environment of intact cells with physiologic concentrations of substrates, co-factors and ...
Manufactured by:Cellworks Research India Private Limited based inBangalore, INDIA
Accelerate drug development timelines, reduce risks and lower costs. Our biosimulation platform predicts human clinical response to investigational drug candidates YEARS earlier than traditional development ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Pooled Human Hepatocytes are the chief functional cells of the liver, responsible for the selective uptake, metabolism and excretion of most drugs. Cells for use in plate cultures or suspension assays represent a key tool for predicting properties such as hepatotoxicity, metabolism, and potential drug-drug interactions. Since these cells mimic ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Prior to clinical trials, it is necessary to conduct animal toxicity studies to best characterize the potential toxicity of new drug candidates. Generally, the objective of preclinical safety evaluation is to determine the toxic effects with respect to target organs, dose dependency, the relationship between clinical findings and exposure to the compound, and ...
Manufactured by:Jubilant Therapeutics Inc. based inBedminster, NEW JERSEY (USA)
collaborations with biotech, pharma, academia, research labs for: Accelerating clinical development and market launch of our ongoing programs. Discovery/development of new programs in synergistic areas. Conducting research with our drug candidates either as monotherapy or in combination to improve existing therapies in cancer and auto-immune disorders. ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Creative Bioarray offers the opportunity for highly predictable pre-clinical cardio-toxicity testing to help our customers to reduce both the cost and duration of bringing a new drug candidate to market. ...
Manufactured by:Inovotion Sas based inLa Tronche, FRANCE
Target validation is an essential and critical phase of the drug discovery process. This is a crucial step before starting to develop a treatment based on a targeted protein that has been identified to play a role in the disease. The target protein’s role must be clearly identified before starting to develop a drug candidate against the ...
by:Molsoft LLC based inSan Diego, CALIFORNIA (USA)
The highly specialized research environments of life science industries require an experienced understanding of the drug discovery process. Many prescription drugs are the result of small molecules that were synthesized in large combinatorial libraries and tested ad hoc against potential targets. This random approach requires substantial capital investment and ...
Manufactured by:Galapagos NV based inMechelen, BELGIUM
This external research can supplement the comprehensive data generated in registration studies by supplying valuable information about the safety, efficacy, pharmacology and tolerability and economic value of our drug candidates and medicines. Galapagos supports external research through unsolicited funding requests. These are evaluated through our Investigator ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Pharmacokinetics (PK) dedicated to determining the mechanisms of a drug's absorption, biodistribution, when it eliminated from the body and what it becomes. It is a study of how an organism affects a drug. In vivo PK studies are critical to ensure drug candidates have appropriate PK properties that can be evaluated in preclinical ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
One of the most important steps in the process of developing a medicine is determining its safety. Alfa Chemistry is dedicated to providing pre-clinical drug research services to support our clients' drug development, pre-clinical and clinical investigations, and assist them in deciding which drug candidates are most worthwhile ...
Manufactured by:CENTOGENE N.V. based inRostock, GERMANY
We work with partners to develop new disease models and new biomarkers of disease. We can also use our disease models to identify new drug targets and screen chemical compounds to identify potential new drug candidates. CENTOGENE provides companies with tools to accelerate drug discovery. From population screening studies that ...
Manufactured by:Ascendia Pharmaceuticals based inNorth Brunswick, NEW JERSEY (USA)
Before conducting pharmaceutical drug product formulation activities, pre-formulation studies are initiated. During the pre-formulation phase, the physical and chemical properties of the active pharmaceutical ingredient (API) are determined. The knowledge gained on the API helps to select the right salt or polymorphic form, and supports the design and development of an initial ...
Manufactured by:ClearLight Biotechnologies, Inc. based inMountain View, CALIFORNIA (USA)
Long before your team will experience commercial success with your brand name drug, preclinical drug development activities take center stage. By the time you submit your investigational new drug (IND) application you’ll want to retire as many risks as possible and have confidence that your experimental drug ...
by:Trion Research GmbH based inPuchheim, GERMANY
Moreover, we offer the full range of preclinical and clinical support from trial design over immunomonitoring and tumor biology analysis to data management and logistics solutions. We are particularly strong in supporting the development of innovative drugs. We work together with our partners to elucidate the modes of action of new compounds and to develop tailored approaches for ...
Manufactured by:Ascendia Pharmaceuticals based inNorth Brunswick, NEW JERSEY (USA)
Parenteral formulation development for drugs delivered by injection or infusion is the fastest and the second most common route of drug administration. These formulations must achieve good compatibility of the drug substances with the excipients and the primary container. Successful formulation development can determine drug ...
by:Trion Research GmbH based inPuchheim, GERMANY
Collaborations - In a team, you do better. We have established long-term partnerships with industry as well as several collaborations with leading academics in the disciplines that are relevant to the projects we support. We draw on the joint capabilities of this network to continuously improve our services and provide optimal assistance for each individual project at any ...
by:PharmAI GmbH based inDresden, GERMANY
Increase your success rate at an early stage. With pharmAI's rapid off-target prediction service you can already find potential off-targets during the discovery ...