Drug Interaction Services
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Manufactured by Newcells Biotech Limitedbased in UNITED KINGDOM
Investigate renal drug transport modalities and drug interactions in vitro. aProximate™ PTCs retain high expression of the relevant transporters involved in drug handling including megalin and cubilin; so are ideal for drug transporter and drug interaction studies of both ...
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Manufactured by Puracypbased in USA
Screening for nuclear receptor activation is a widely used and accepted practice to predict adverse drug effects and drug-drug interactions. Moreover, assessing nuclear receptor activation meets the latest FDA guidance for industry on Drug-Drug Interactions. Receptor activation ...
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Manufactured by Creative Bioarraybased in USA
Pooled Human Hepatocytes are the chief functional cells of the liver, responsible for the selective uptake, metabolism and excretion of most drugs. Cells for use in plate cultures or suspension assays represent a key tool for predicting properties such as hepatotoxicity, metabolism, and potential drug-drug interactions. Since ...
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by InterXbased in USA
InterX operates at the nexus of academic research and pharma-tech industry. We partner with leading edge researchers, drug developers, and biotechnology companies across the globe to predict drug-target interactions using the most advanced computer algorithms ...
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based in USA
CTEH®’s pharmacology & toxicology professionals have extensive experience assessing the human toxicity of drugs and chemicals, and drug interactions and adverse reactions. CTEH® provides additional experience in pharmacokinetic analysis. Levels of drugs or chemicals in blood and/or urine are frequently key ...
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Manufactured by Alfa Chemistrybased in USA
Early studies on the properties of drugs in ADMET mainly focused on human-derived or humanized tissue functional proteins as drug targets. Combined with in vitro research techniques and computer simulation, scientists study the interaction between drugs and in vivo biophysical and biochemical barrier factors. Alfa Chemistry can ...
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Manufactured by Invicro, LLCbased in USA
Invicro’s early clinical imaging services deliver decision-making data for drug development teams in Phases 0, I and II. We have many years of pharma industry experience, and this understanding of the drug development process helps us design and execute pathology and imaging studies so that the resultant data reduces risk in later ...
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based in USA
Helix Diagnostics pharmacogenomics testing identifies unique variances on gene markers to determine an individual’s response to particular medications to create better treatment plans and improve outcomes. Reviewing patients genetic profile allows a much more personalized medicine approach and eliminates trial and error for more effective, quicker and safer therapies. ...
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Manufactured by BioVariance GmbHbased in GERMANY
The goal of personalized medicine is to prescribe the most suitable medication in the optimal dosage for each individual patient. To achieve this, physicians rely not only on medical diagnoses that take the personal characteristics of a patient into account but can now also engage modern tools of molecular diagnostics. Such genetic analyses can provide essential information to fully identify the ...
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Manufactured by CN Biobased in UNITED KINGDOM
Employing our Liver-on-a-chip hepatic co-culture model (evaluated by our collaborators at the U.S. FDA), our DILI in vitro Service can screen your small molecules, antibodies, ASO, and gene editing reagents to establish human DILI ...
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Manufactured by Newcells Biotech Limitedbased in UNITED KINGDOM
Cross-species comparison of drug handling with near-physiological kidney transporter model. New drug molecules are usually tested in vivo in two preclinical species to gain a more detailed understanding of how they are transported and eliminated through the kidney and also to mitigate risk of renal toxicity in humans. However, these animal ...
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Manufactured by Charles Riverbased in USA
Discovering and characterizing novel drug candidates for preclinical development depends on innovative and reliable science. Our unique combination of integrated, multidisciplinary drug discovery expertise and unparalleled scope of capabilities in targets, platforms, and therapeutic areas allow us to deliver depth and breadth in science with ...
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Manufactured by InnoSer Belgie NVbased in BELGIUM
We optimize your lead compounds using expertise and data-driven decisions. The lead optimization stage marks the end of the drug discovery phase and the start of pharmaceutical or biological development. Insight into the absorption, distribution, metabolism, and excretion (ADME) is key to progressing your identified lead compounds after the ...
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Manufactured by in.vent Diagnostica GmbHbased in GERMANY
engine is your reliable partner for the analysis of your sample. Our protein array screening service covers the analysis of positive interactions up to antigen identification. In a single experiment it is possible to screen your sample for interactions with more than 10,000 antigens. Our fast method is non-biased and guarantees maximum ...
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Manufactured by Creative Bioarraybased in USA
Creative Bioarray provides various in vitro ADME/PK services including high-throughput ADME screening, in vitro metabolism, in vitro permeability and transporter assays. ADME is short for "absorption, distribution, metabolism, and excretion". The four properties determine the drug level within a body, the drug exposure to ...
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Manufactured by Cloud-Clone Corp.based in USA
Pharmacokinetics mainly study dynamic changes of drug metabolism in body, including drug absorption, distribution and excretion. The research will analyze the drugs and their metabolites by collecting samples in different tissues, organs at different time point. The pharmacokinetic experiments in vivo and in vitro can be designed ...
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based in USA
1 PCR Test Swab gives you: Detection of 30 Pathogens. Patient-Specific Antibiotic Resistance. 99% Accurate Results in 72 Hours. ...
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by Inotivbased in USA
Inotiv offers a broad scope of expertise for drug metabolism and pharmacokinetics (DMPK) studies at all stages of R&D, from lead optimization through NDA. Benefit from our long and impeccable regulatory history, world-class team of scientists, and 40+ year track record of providing leading pharma and biotech companies with attentive, ...
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