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Drug Toxicity Services
17 services found
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Accelerated in vitro evaluation of retinal toxicity. Newcells offers a fast and reliable retinal drug toxicity in vitro testing service using complex models developed in house: retinal organoids and RPE. The retinal toxicity service evaluates how new compounds affect cell viability, following photoreceptor degeneration or loss of ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The construction of an antibody-drug conjugate (ADC) is the covalent coupling of a monoclonal antibody and a toxic payload drug via a linker molecule. The ultimate goal for an ADC development project is to deploy the resulted ADC into in vivo systems, both in model animals and eventually human patients, to cure cancer and other diseases utilizing ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Pooled Human Hepatocytes are the chief functional cells of the liver, responsible for the selective uptake, metabolism and excretion of most drugs. Cells for use in plate cultures or suspension assays represent a key tool for predicting properties such as hepatotoxicity, metabolism, and potential drug-drug interactions. Since these cells mimic ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The construction of an antibody-drug conjugate (ADC) is the covalent coupling of a monoclonal antibody and a toxic payload drug via a linker molecule. The ultimate goal for an ADC development project is to deploy the resulted ADC into in vivo systems, both in model animals and eventually human patients, to cure cancer and other diseases utilizing ...
by:Center for Toxicology and Environmental Health, L.L.C. (CTEH) based inNorth Little Rock, ARKANSAS (USA)
CTEH®’s pharmacology & toxicology professionals have extensive experience assessing the human toxicity of drugs and chemicals, and drug interactions and adverse reactions. CTEH® provides additional experience in pharmacokinetic analysis. Levels of drugs or chemicals in blood and/or urine are frequently key ...
by:Intertox, Inc. based inSeattle, WASHINGTON (USA)
FDA Liaison – Provide guidance and/or serve as a direct liaison with the FDA for the coordination of Prescription Drug User Fee Act meetings. Non-clinical Regulatory Support – Manage Investigational New Drug Applications’ toxicity studies, associated non-clinical safety studies, and biological activity programs to support ...
by:Strateos Inc. based inMenlo Park, CALIFORNIA (USA)
High throughput screening (HTS) in drug discovery is critical for drug discovery and is a widely used tool for querying small molecule chemical libraries to determine the structure-activity relationship (SAR) of molecules and helps drive the development of specific and potent bioactive ...
Manufactured by:Ascendia Pharmaceuticals based inNorth Brunswick, NEW JERSEY (USA)
Nanotechnology is now being extensively utilized in the development of innovative drug delivery systems for various routes of administration. Due to the advantages of their targeted drug delivery, reduced toxicity, long circulation, and enhanced half-life, nanoparticles are particularly useful for use in long acting formulations. ...
Manufactured by:Veracyte based inMarseille Cedex 9, FRANCE
The Cancer Immune Atlas creates a reference database from individual Immunograms, to generate biomarker maps, assess toxicity and drug response, stratify patients, and develop predictive ...
Manufactured by:Creative BioMart based in, NEW YORK (USA)
Creative Biomart provides drug analysis service for pre-clinical drugs and natural products on their physical and chemical properties. Our services include three main assays: pre-clinical pharmaceutical property analysis, pharmacokinetics analysis & bioanalysis, andnatural product ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Creative Bioarray provides various in vitro ADME/PK services including high-throughput ADME screening, in vitro metabolism, in vitro permeability and transporter assays. ADME is short for "absorption, distribution, metabolism, and excretion". The four properties determine the drug level within a body, the drug exposure to tissues, and the metabolic process of a compound, which can help predict ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
With ongoing advancements in proteomics mass spectrometry technology, there has been a notable increase in the precision of analytical instruments, resulting in a richer dataset. While this detailed protein data is invaluable for deeper scientific investigation, the vast volumes of data produced by high-throughput proteomic screenings introduce substantial challenges in analyzing protein sample ...
Manufactured by:Inovotion Sas based inLa Tronche, FRANCE
Pharmaceutical chemical and biology researchers need to develop new methods and models to improve the predictivity of preclinical discovery phases and increase the number of good molecules in clinic. INOVOTION’s unique in vivo technology will allow you to raise the global number of drug candidates tested in clinic without increasing your ...
by:Activation Laboratories Ltd. based inAncaster, ONTARIO (CANADA)
Our scientists are highly experienced in both implementing client assays and developing them de novo. Our Canadian laboratories undergo routine audits from both regulatory agencies and clients alike. Our In Vitro Assay Service and Cell Based Bioassays Services include ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
MtoZ Biolabs offers highly sensitive and accurate Antibody-Drug Conjugate (ADC) Analysis service based on high-throughput liquid chromatography and high-resolution mass spectrometer ...
Manufactured by:Altis Biosystems based inDurham, NORTH CAROLINA (USA)
Accurate biological screening based on real human intestinal tissue, with a standardized workflow for reliable and reproducible data, RepliGut represents ?the next generation for in vitro testing with faster actionable data. ...
Manufactured by:CD Bioparticles based inShirley, NEW YORK (USA)
CD Bioparticles offers one-stop drug-carrier complex analysis package service including drug in vitro testing using advanced techniques. Our experienced scientists have created a comprehensive platform to measure the drug in vitro testing from different ...