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Epitope Services

19 services found

Epitope Selection & Validation Service

Epitope Selection & Validation Service

Manufactured by:Sanquin   based inAmsterdam, NETHERLANDS
Our proprietary technology for UV-induced MHC-peptide exchange is ideally suited for high-throughput screening of peptide-binding to the MHC class I complexes. Moreover, combinatorial coding enables fast finding of relevant peptide-specific cytotoxic T ...
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Human Testing Services

Human Testing Services

Manufactured by:POP Biotechnologies, Inc. (POP BIO)   based inBuffalo, NEW YORK (USA)
CoPoP GLP toxicity report available. CoPoP is part of EuCorVac-19, tested in a 280 person ph1/2 trial. Testing framework for human ...
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Immunotherapy Services

Immunotherapy Services

Manufactured by:POP Biotechnologies, Inc. (POP BIO)   based inBuffalo, NEW YORK (USA)
SNAP liposomes contain synthetic MPLA, QS-21 and Cobalt porphyrin phospholipid (CoPoP). CoPoP enables liposomes to stably bind short MHC-I epitopes upon admixture. Better delivery of epitopes and adjuvants to immune cells in draining lymph nodes. Induce higher frequency of antigen specific CD8+ T cells with > 10,000X lower peptide ...
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Nanobody (VHH) Library Generation Services

Nanobody (VHH) Library Generation Services

by:Biointron   based inShanghai, CHINA
Nanobodies are distinguished from other conventional antibody formats by their unique properties of size, solubility, intrinsic stability, easy tailoring into pluripotent constructs, recognition of uncommon or hidden epitopes, binding into cavities or active sites of enzyme targets, ease and speed of drug discovery, and ease of manufacture. BioIntron is a well-recognized leader ...
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Mouse Monoclonal Antibody Development Services

Mouse Monoclonal Antibody Development Services

Manufactured by:Antibodies Incorporated   based inDavis, CALIFORNIA (USA)
The monoclonal antibodies produced have broad utility as therapeutics, diagnostic tools, and research reagents. The approach enables discovery of antibodies that bind to a variety of epitopes on the target molecule and, coupled with a robust screening platform, allows for identification of clones with the most desirable characteristics. ...
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MtoZ Biolabs - Tumor-Associated Antigens 1 Screening Service

MtoZ Biolabs - Tumor-Associated Antigens 1 Screening Service

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
T cells play a vital role in destroying pathogens and monitoring pathological cells. They are able to distinguish between self-antigens and non-self-antigens by surface T cell receptors (TCRs). Most human T cells express the classical TCRs, which consists of TCRα and TCRβ chains co-expressed with CD3 chains (γ, δ, ε, and ζ). ...
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Custom Monoclonal Antibody Production Service

Custom Monoclonal Antibody Production Service

Manufactured by:Rockland Immunochemicals, Inc.   based inLimerick, PENNSYLVANIA (USA)
Our list of services includes antigen consultation, peptide or protein antigen production, antibody generation, antibody purification, and conjugation to reporter molecules such as peroxidase or fluorochromes. We are experts in generating antibodies specific for post-translational modifications—including phospho-epitopes, acetylation, methylation, hydroxylation, ...
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Targeting Disease Therapy

Targeting Disease Therapy

Manufactured by:MODAG GmbH   based inWendelsheim, GERMANY
The misfolding/ aggregation pathway resulting in amyloid fibrils involves characteristic oligomer species which have been shown to be the most relevant toxic protein species. These pathological oligomers exhibit structural epitopes that are not found in physiologically folded proteins or physiological protein assemblies, providing a specific structural target for anle138b, our ...
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Antibody Drug Conjugate Services

Antibody Drug Conjugate Services

by:Revvity Gene Delivery (formerly SIRION Biotech)   based inHamburg, GERMANY
In the discovery of oncology therapeutics, Antibody-drug conjugates (ADCs) are rapidly gaining momentum, with hundreds of candidates advancing through clinical development. Whether your priority lies in assessing the epitope binding of your construct, evaluating the cytotoxic potency of the payload, or scrutinizing the efficacy of the linker in cleaving, each facet demands ...
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MtoZ Biolabs - Antibody-Antigen Interactions Characterization Service | HDX-MS

MtoZ Biolabs - Antibody-Antigen Interactions Characterization Service | HDX-MS

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Monoclonal antibodies (mAbs) are powerful therapeutic tools. These glycoproteins, belonging to the immunoglobulin (Ig) family, are utilized by the immune system to identify and neutralize foreign organisms or antigens. Ig’s are classified in five groups, IgA, IgD, IgE, IgG, and IgM (as α, δ, ε, γ, and μ), based on the structure of their constant regions. Among these, IgG subtypes—predominantly ...
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1D Antibody Sequence Analysis Service

1D Antibody Sequence Analysis Service

by:Ab Studio Inc.   based inHayward, CALIFORNIA (USA)
1D antibody sequence analysis service with licensed software and in-house ...
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Antibody Affinity Measurement Services

Antibody Affinity Measurement Services

Manufactured by:Creative Biolabs   based inShirley, NEW YORK (USA)
Label-free interaction analysis is of great importance for scientists to study interactions between biomolecules. Scientists from Creative Biolabs are competent for performing antibody affinity and kinetics measurement with the most advanced Biacore, ProteOn, Octet systems, etc. These systems are mainly based on the optical phenomena technologies - surface plasmon resonance (SPR) and bio-layer ...
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Sheep Monoclonal Antibodies (SMAs) Services

Sheep Monoclonal Antibodies (SMAs) Services

Manufactured by:Bioventix Plc   based inSurrey, UNITED KINGDOM
Bioventix has created a novel sheep hybridoma technology to produce stable and productive cell lines that secrete sheep monoclonal antibodies (SMAs) of very high affinity. The ultra-high affinity of Bioventix’s antibodies facilitates the development of immunoassays of increased sensitivity and precision at Bioventix’s ...
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Nanobody Production Services

Nanobody Production Services

Manufactured by:Echelon Biosciences, Inc (EBI)   based inSalt Lake City, UTAH (USA)
Nanobodies are single domain antibodies produced from camelids by immunization with a target antigen, similar to the process used in mice and rabbits for traditional antibody generation. However, because of the single heavy chain found in camelid antibodies, cDNAs can be generated from this single domain which can then be expressed recombinantly. This opens up a wide variety of applications that ...
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Antibody Humanization and Optimization Services

Antibody Humanization and Optimization Services

by:Ab Studio Inc.   based inHayward, CALIFORNIA (USA)
Humanization percentage, CDR Immunogenicity, Antigen binding affinity, Antibody expression level, Aggregation potential, Antibody stability, ...
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Reagent Development Services

Reagent Development Services

Manufactured by:Global Access Diagnostics (GADx)   based inThurleigh (Bedfordshire), UNITED KINGDOM
GADx has produced hundreds of rare biomolecules for clients and for our own in-house development. Our expertise is in the production of highly specific and well characterized reagents including those used in immunoassays where performance is directly related to reagent sensitivity, specificity and purity. We have deep experience in developing or sourcing high affinity antibodies and controlling ...
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Custom Monoclonal Antibody Preparation Services

Custom Monoclonal Antibody Preparation Services

Manufactured by:Synbio Technologies LLC   based in, NEW JERSEY (USA)
Hybridoma technology features the effective usage of innate functions of both immune and cancer cells to generate monoclonal antibodies (mAbs). The resulting hybridoma cell lines are produced to combat specific antigens of interest. Such technology has forged remarkable new approaches toward therapeutic mAb discovery, as well as disease diagnosis and ...
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Creative Peptides - Glycopeptides Synthesis Services

Creative Peptides - Glycopeptides Synthesis Services

Manufactured by:Creative Peptides   based inNew York, NEW YORK (USA)
On the basis of extensive experience in peptide synthesis, Creative Peptides proudly offers the most comprehensive glycopeptides synthesis services to our worldwide clients. Our scientists are committed to deliver high quality glycopeptides which will go through strict mass spectral and HPLC analysis to meet our customers’ demands. ...
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Immuno-Oncology

Immuno-Oncology

Manufactured by:Kiadis Pharma NV   based inAmsterdam, NETHERLANDS
Innovative antibody-based molecular concepts. New treatments for cancer that leverage our own immune system to attack and destroy cancer cells can provide long-term and durable therapeutic responses in patients suffering from life-threatening malignancies. These benefits for patients have been driven by recently developed therapeutic antibodies binding with high specificity to drug targets on ...
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