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Neurodegenerative Services
30 services found
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Amyotrophic lateral sclerosis is a neurodegenerative disorder leading to loss of voluntary muscle movement, paralysis, and eventually death. There is now an urgent need for the development of effective treatment for ALS. ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
Neurodegenerative diseases (NDs) comprise a diverse set of pathological processes involving progressive neuronal dysfunction, degeneration, and death, leading to incurable and debilitating diseases. Creative Biogene provides a comprehensive range of services and products to assist researchers in neurodegeneration-related mitochondria ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
Creative Biogene provides the fractionated mitochondrial magnetic separation (FMMS) method to increase the production of brain-derived mitochondria compared with the UC method and can better detect mitochondrial damage in the central nervous system injury and neurodegenerative ...
Manufactured by:RareStone Group based inShanghai, CHINA
Rare neurological diseases include developmental defects of the nervous system, genetic and metabolic diseases, neuroimmune diseases, neurological tumors, special types of infectious diseases of the nervous system, neurodegenerative diseases, and neuromuscular diseases. At present, more than 7,000 rare diseases have been found in humans, about 60% of which are neurological ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Multiple Sclerosis (MS) is a chronic inflammatory neurodegenerative disease of the central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) is the most common animal model of human MS as it is especially useful to investigate neuroinflammatory pathways and often serves as a "proof-of-principle" model for the efficacy of novel treatment strategies. ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Autophagy is a key catabolic process that ensures the removal of excess or damaged cellular components under physiological and pathological conditions, and provides a metabolic supply in the absence of extracellular nutrients, thereby maintaining the proper balance of cells. Optimal autophagy activity plays an important protective role in several human diseases, such as ...
by:Neuron Experts based inMarseille, FRANCE
To keep up its high level of Competitiveness, Neuron Experts constantly develops new cellular models to provide the most accurate answers to customers’ needs: Development of new neurodegenerative disease models following current discoveries of new therapeutic targets, Development of new cellular models to study interaction between neurons and skin, Development of human ...
Manufactured by:MODAG GmbH based inWendelsheim, GERMANY
Multiple System Atrophy (MSA) is a rare neurodegenerative disorder that belongs to the group of synucleinopathies and is also classified as an “atypical parkinsonism” disorder. Pathologically, MSA is characterized by abnormal deposits of the α-synuclein protein mainly in oligodendroglial cells and also in certain nerve cells. ...
Manufactured by:Neurodigitech, LLC based inEncinitas, CALIFORNIA (USA)
The NDT teams in specialized in both non-GLP and GLP compliant pre-clinical assessments of CNS disease therapeutics using a variety of biomarkers, including histology, immunohistochemical and histochemical methods. In particular, NDT is dedicated to custom-designed neuropathological assessments for the neurodegenerative diseases, such as Alzheimer's, Parkinson's, ALS, and brain ...
by:Azafaros based inNaarden, NETHERLANDS
They typically present in infancy and childhood, although adult-onset forms also occur. Most LSDs have a progressive neurodegenerative clinical course, although symptoms in other organ systems are frequent. LSD-associated genes encode different lysosomal proteins, including lysosomal enzymes and lysosomal membrane protein (Platt et al, ...
Manufactured by:GS International Trade Co.,Ltd based in, CHINA
Organic Synthesis Used as a precursor for synthesizing esters, amides, and other derivatives via epoxide ring-opening reactions. Drug Development Explored for its potential in treating cancers, neurodegenerative diseases, and as a drug carrier. Biochemical Research Studied for antimicrobial and anti-inflammatory activities in experimental models. Other Hot Sale CAS: CAS: ...
by:Vaiomer based inLabège, FRANCE
Complex disorders are multifactorial and often chronic, caused by genetic and environmental factors and comprising hundreds of conditions from cardio-metabolic diseases to neurodegenerative and mental disorders. These pathologies commonly present a low- to high-grade inflammation and have been associated with gut microbiota dysbiosis or a distinct microbial signature. However, ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
"Knocking out" related mammalian genes is an important method for studying gene function or its potential as a drug target, widely used in research on neurodegenerative diseases such as Alzheimer's disease, cancer, cardiovascular diseases, inflammation, or metabolic diseases. CRISPR/Cas9 is a revolutionary gene-editing technology that can precisely modify the genomic sequence. ...
Manufactured by:Neuron Bio based inGranada, SPAIN
Neuron Biolabs develops biosolutions for application in the pharmaceutical and agri-food industries through its specialised divisions. The Pharma division is dedicated fundamentally to the search for preventative drugs and treatments for neurodegenerative diseases, particularly Alzheimer’s disease. The Diagnostic division develops tools and biomarkers for the diagnosis of ...
Manufactured by:Advanced Brain Monitoring, Inc. based inCarlsbad, CALIFORNIA (USA)
Biomarker specializations include Alzheimer’s and dementia, Parkinson’s and basal ganglia disorders, mood disorders and other neurodegenerative and neuropsychiatric diseases. ...
by:IOS Press based inAmsterdam, NETHERLANDS
Here you will find information about our ejournals and ebooks in terms of collections/subject areas, pricing, terms and conditions and a FAQ ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
PROTACs can not only offer potential therapeutic applications for a variety of conditions, including cancer, immune dysregulation, viral infections, and neurodegenerative ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
PROTACs can not only offer potential therapeutic applications for a variety of conditions, including cancer, immune dysregulation, viral infections, and neurodegenerative diseases, but also provide a unique chemical knockdown tool for biological research in a catalytic, ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Human iPSC-derived Microglia provide a reproducible, physiologically-relevant model in an easy-to-use, assay-ready format for investigating neuroglia involvement in neurodegeneration and neurodevelopment. We also offer a fully optimized serum-free Microglia Maintenance Medium to promote and support the maintenance of microglia. The method for generating iPSC-derived microglia mimics the in vivo ...
by:Neuron Experts based inMarseille, FRANCE
Advice in the preclinical development of new neuro-active compounds. The Neuron Experts team (operational and scientific) provides support and advice in your R&D programs and also in the development of new molecules in specific disease indications. ...