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Mtoz Biolabs Nucleic Acid Services

6 services found

MtoZ Biolabs - Antibody De Novo Sequencing Service for R&D | Mass Spec

MtoZ Biolabs - Antibody De Novo Sequencing Service for R&D | Mass Spec

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Antibodies bind to various antigens with high affinity and specificity, playing a crucial role in adaptive immune response to infections and can also mediate autoimmune diseases by targeting self-antigens. Antibodies facilitate immunity by inhibiting critical stages of a pathogen's replication cycle, such as receptor binding and cellular entry, activating the complement system, or initiating ...
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MtoZ Biolabs - Molecular Glue Screening Service | PROTAC Service

MtoZ Biolabs - Molecular Glue Screening Service | PROTAC Service

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Proteins play a pivotal role in the regulation, function, and structure of various human organs and tissues. The regulation of the synthesis and degradation of proteins is crucial for cell functionality. Protein turnover can exist in three states: equilibrium, pool expansion, and pool contraction. At equilibrium, the rate of protein synthesis matches that of degradation, leading to unchanged ...
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MtoZ Biolabs - Protein Corona-Mediated Nanomedicine Targeted Delivery Service

MtoZ Biolabs - Protein Corona-Mediated Nanomedicine Targeted Delivery Service

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Nanoparticles (NPs) undergo interactions with serum proteins during systemic administration, which may result in the formation of protein corona (PC). Investigating the interplay between the chemical and biological properties of NPs enhances clinical translation efficiency. NPs with PC can be considered to exhibit a distinct biological ...
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MtoZ Biolabs - Immunotherapy Target Discovery Service

MtoZ Biolabs - Immunotherapy Target Discovery Service

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Tumor immunotherapy utilizes active or passive methods to provoke tumor-specific immune responses in the body, harnessing their inhibitory and cytotoxic functions against tumor cells. Characterized by its specificity, efficacy, and mitigation of collateral damage, immunotherapy distinguishes itself from conventional methods such as surgery, targeted therapy, and ...
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MtoZ Biolabs - Eukaryotic Transcriptome Sequencing Service

MtoZ Biolabs - Eukaryotic Transcriptome Sequencing Service

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Transcriptome sequencing involves sequencing the complete mRNA within cells during specific developmental stages or physiological conditions. This technique aids in studying gene expression levels and gene structure at a comprehensive level, elucidating molecular mechanisms in specific biological processes. It is widely applied in basic research, clinical diagnosis, drug development, and ...
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MtoZ Biolabs - Degrader Design and Synthesis | PROTAC Service

MtoZ Biolabs - Degrader Design and Synthesis | PROTAC Service

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
PROTACs represent a novel strategy for protein degradation that has gained prominence recently. Utilizing bifunctional molecules, PROTACs enable the targeted ubiquitination and subsequent degradation of proteins via the UPS. PROTACs can not only offer potential therapeutic applications for a variety of conditions, including cancer, immune dysregulation, viral infections, and neurodegenerative ...
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