Show results for
Refine by
Pathology Disease Services
6 services found
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
We mainly use the three approaches to abrogate gene function in zebrafish: stable lines carrying mutations (mutants); morpholino-based knock-down of gene function; and use of CRISPR/Cas9 gene editing to disrupt gene function in injected embryos. Many human pathological conditions from Alzheimer's disease to metabolic syndrome have been successfully modelled in ...
Manufactured by:MODAG GmbH based inWendelsheim, GERMANY
Certain proteins including α-synuclein can form disease-specific fibrillar amyloid aggregates. The misfolding/ aggregation pathway resulting in amyloid fibrils involves characteristic oligomer species which have been shown to be the most relevant toxic protein species. These pathological oligomers exhibit structural epitopes that are not found in ...
by:Vaiomer based inLabège, FRANCE
Bacterial translocation: the missing link between intestinal microbiome and human complex non-communicable diseases. Complex disorders are multifactorial and often chronic, caused by genetic and environmental factors and comprising hundreds of conditions from cardio-metabolic diseases to neurodegenerative and mental disorders. These pathologies ...
by:Oncimmune Holdings PLC based inNottingham, UNITED KINGDOM
Autoimmune disease is caused by the breaking of self-tolerance. Oncimmune’s understanding of the immune system as a mediator of disease powers the ImmunoINSIGHTS service for autoimmune ...
by:Orthogen AG based inDüsseldorf, GERMANY
We co-pioneered the discovery and importance of biomolecular and biochemical as underlying key mechanisms. These processes are universal and generally apply to tissue aging as well as pathologies –independent of tissue and disease type– such as oncologic, cardiovascular, autoimmune, dermatologic and orthopedic diseases. With these ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Sphingolipids are fundamental structural components of cell membranes, forming lipid rafts by combining with other components. Sphingolipids are involved in regulating biological processes such as cell growth, differentiation, and apoptosis. Ceramide is the central hub of the sphingolipid pathway, including sphingomyelin, glucosylceramide, and galactosylceramide, and is mainly divided into ...