Pharmacokinetic Services
34 services found
by:SGS M-SCAN Ltd based inWokingham, UNITED KINGDOM
With over 25 years of experience and operating out of three GLP compliant laboratories, SGS’s Life Science Services provides pharmacokinetic analysis and bioanalytical services with a dedicated team of specialists. Pharma and biotech companies of all sizes have chosen us as the preferred bioanalytical partner. SGS has the expertise to both develop assays de novo (including ...
by:Center for Toxicology and Environmental Health, L.L.C. (CTEH) based inNorth Little Rock, ARKANSAS (USA)
CTEH® provides both traditional pharmacokinetic modeling and physiologically-based pharmacokinetic (PBPK) modeling. CTEH® toxicologists are experienced in developing and applying traditional and PBPK modeling to reconstruct exposure and dose, support the establishment of health-based guidelines, and improve dose-response characterizations for assessments ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Pharmacokinetics (PK) studies provide critical information regarding the behavior of a drug in circulation and its ultimate form after extensive in vivo metabolism. Results from PK studies often serve as guidelines for clinical trials designs, especially in the development of an antibody-drug conjugate (ADC). Due to the heterogeneous nature of ADCs, multiple analytes have to be ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Creative Bioarray provides various in vitro ADME/PK services including high-throughput ADME screening, in vitro metabolism, in vitro permeability and transporter assays. ADME is short for "absorption, distribution, metabolism, and excretion". The four properties determine the drug level within a body, the drug exposure to tissues, and the metabolic process of a compound, which can help predict ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Pharmacokinetics (PK) studies provide critical information regarding the behavior of a drug in circulation and its ultimate form after extensive in vivo metabolism. Results from PK studies often serve as guidelines for clinical trials designs, especially in the development of an antibody-drug conjugate (ADC). Due to the heterogeneous nature of ADCs, multiple analytes have to be ...
Manufactured by:Cloud-Clone Corp. based inKaty, TEXAS (USA)
Pharmacokinetics mainly study dynamic changes of drug metabolism in body, including drug absorption, distribution and excretion. The research will analyze the drugs and their metabolites by collecting samples in different tissues, organs at different time point. The pharmacokinetic experiments in vivo and in vitro can be designed according to customers’ ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
ADMET stands as an abbreviation for absorption, distribution, metabolism, excretion, and toxicity in pharmacokinetics and pharmacology. These properties describe the reaction of a drug medication within an organism, human, or animal, which helps scientists evaluate their drug candidates and select compounds that are likely to have the desired effects on patients. ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
A large variety of animal models has been developed to provide investigators with the ability to characterize the pharmacokinetics and pharmacodynamics of ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Pharmacokinetics (PK) dedicated to determining the mechanisms of a drug's absorption, biodistribution, when it eliminated from the body and what it becomes. It is a study of how an organism affects a drug. In vivo PK studies are critical to ensure drug candidates have appropriate PK properties that can be evaluated in preclinical pharmacology and safety studies. In vivo PK ...
Manufactured by:CD Formulation based in, NEW YORK (USA)
Solubility and bioavailability issues run through drug metabolism and pharmacokinetic evaluation of candidate compounds, preclinical prescription development, and commercial formulation development. From the toxicological evaluation stage, CD Formulation has a perfect drug metabolism and pharmacokinetic support system, each experiment only consumes ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Lead optimization is a complex and iterative process for identifying an improved drug lead with the goal of progressing to a preclinical candidate by altering the chemical structure of a confirmed hit. A diversity of properties such as target’s specificity, selectivity, pharmacodynamics, pharmacokinetics and toxicological properties are improved by modifying the chemical ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
The structure of small molecule inhibitors has good spatial dispersion, and their chemical properties determine their good pharmacodinemic properties and pharmacokinetic properties. These characteristics make small molecule inhibitors show great advantages in drug research and development process, and these molecules are becoming more and more popular in the ...
by:Center for Toxicology and Environmental Health, L.L.C. (CTEH) based inNorth Little Rock, ARKANSAS (USA)
CTEH®’s pharmacology & toxicology professionals have extensive experience assessing the human toxicity of drugs and chemicals, and drug interactions and adverse reactions. CTEH® provides additional experience in pharmacokinetic analysis. Levels of drugs or chemicals in blood and/or urine are frequently key pieces of information in accidents, worker exposure ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Combined with in vitro research techniques and computer simulation, scientists study the interaction between drugs and in vivo biophysical and biochemical barrier factors. Alfa Chemistry can predict ADME parameters and pharmacokinetic properties by calculating the physical and chemical indicators of one or more small molecules. We also study the drug-like properties and ...
Manufactured by:CD Formulation based in, NEW YORK (USA)
CD Formulation researchers have conducted extensive research and development of drug delivery systems (DDS) in order to improve the pharmacokinetics and pharmacodynamics of drugs by delivering the required dose at the target site at the appropriate time and rate. Our drug delivery system development offerings include nanoparticles and particles, transdermal patches, and more. ...
Manufactured by:Cambrex Corporation based inEast Rutherford, NEW JERSEY (USA)
Cambrex has extensive experience in Drug Metabolism and Pharmacokinetic (DMPK), Bioanalytical and Biopharmaceutical Analyses. The Biopharmaceutical Analyses scope supports GMP method development, validation, and routine analysis including but not limited to host cell proteins, host cell DNAs, endotoxins, enzyme kinetics, and even bacteriophage titering assays. The Drug Metabolism ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Alfa Chemistry is dedicated to providing pre-clinical drug research services to support our clients' drug development, pre-clinical and clinical investigations, and assist them in deciding which drug candidates are most worthwhile to pursue in clinical trials. We emphasize pharmacology, pharmacokinetics, medication safety assessment, and bioanalytical services in our customized ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Biosimilars are biological products that are highly similar to an approved original biological drug (reference or brand drug) without any clinically meaningful differences in quality, safety, or efficacy compared to those approved. Biosimilars typically enter the market after the patent protection period of the original drug has expired, providing a more cost-effective treatment ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
PROTACs represent a novel strategy for protein degradation that has gained prominence recently. Utilizing bifunctional molecules, PROTACs enable the targeted ubiquitination and subsequent degradation of proteins via the UPS. PROTACs can not only offer potential therapeutic applications for a variety of conditions, including cancer, immune dysregulation, viral infections, and neurodegenerative ...
Manufactured by:Creative BioMart based in, NEW YORK (USA)
Creative Biomart provides drug analysis service for pre-clinical drugs and natural products on their physical and chemical properties. Our services include three main assays: pre-clinical pharmaceutical property analysis, pharmacokinetics analysis & bioanalysis, andnatural product ...