Pharmacokinetic Services
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Manufactured by Creative Biolabsbased in CHINA
Pharmacokinetics (PK) models are generated to elucidate the transformations that a drug undergoes in an organism and the rules that determine this ...
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based in UNITED KINGDOM
With over 25 years of experience and operating out of three GLP compliant laboratories, SGS’s Life Science Services provides pharmacokinetic analysis and bioanalytical services with a dedicated team of specialists. Pharma and biotech companies of all sizes have chosen us as the preferred bioanalytical partner. SGS has the expertise to ...
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based in USA
CTEH® provides both traditional pharmacokinetic modeling and physiologically-based pharmacokinetic (PBPK) modeling. CTEH® toxicologists are experienced in developing and applying traditional and PBPK modeling to reconstruct exposure and dose, support the establishment of health-based guidelines, and improve dose-response ...
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Manufactured by Creative Biolabsbased in CHINA
Pharmacokinetics (PK) studies provide critical information regarding the behavior of a drug in circulation and its ultimate form after extensive in vivo metabolism. Results from PK studies often serve as guidelines for clinical trials designs, especially in the development of an antibody-drug conjugate (ADC). Due to the heterogeneous ...
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Manufactured by Creative Biolabsbased in CHINA
Pharmacokinetics (PK) studies provide critical information regarding the behavior of a drug in circulation and its ultimate form after extensive in vivo metabolism. Results from PK studies often serve as guidelines for clinical trials designs, especially in the development of an antibody-drug conjugate (ADC). Due to the heterogeneous ...
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Manufactured by Proteomics Internationalbased in AUSTRALIA
Comprehensive suite of new pre-clinical and clinical testing capabilities: pharmacokinetic (PK), pharmacodynamic (PD), and companion diagnostic (CDx) services. Proteomics International applies its proven expertise and experience in targeted mass spectrometry to the field of PK testing. Mass spectrometry is ideal for the accurate and ...
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Manufactured by Creative Bioarraybased in USA
Creative Bioarray provides various in vitro ADME/PK services including high-throughput ADME screening, in vitro metabolism, in vitro permeability and transporter assays. ADME is short for "absorption, distribution, metabolism, and excretion". The four properties determine the drug level within a body, the drug exposure to tissues, and the metabolic process of a compound, which can help predict ...
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Manufactured by Cloud-Clone Corp.based in USA
Pharmacokinetics mainly study dynamic changes of drug metabolism in body, including drug absorption, distribution and excretion. The research will analyze the drugs and their metabolites by collecting samples in different tissues, organs at different time point. The pharmacokinetic experiments in vivo and in vitro can be designed ...
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Manufactured by Bexson Biomedicalbased in USA
We are developing a formulation technology platform & a subcutaneous delivery platform for controlled delivery of critical medications in need of pharmacokinetic ...
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Manufactured by Creative Biolabsbased in CHINA
ADMET stands as an abbreviation for absorption, distribution, metabolism, excretion, and toxicity in pharmacokinetics and pharmacology. These properties describe the reaction of a drug medication within an organism, human, or animal, which helps scientists evaluate their drug candidates and select compounds that are likely to have the ...
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Manufactured by Alfa Chemistrybased in USA
Lead optimization is a complex and iterative process for identifying an improved drug lead with the goal of progressing to a preclinical candidate by altering the chemical structure of a confirmed hit. A diversity of properties such as target’s specificity, selectivity, pharmacodynamics, pharmacokinetics and toxicological properties are ...
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Manufactured by Creative Biolabsbased in CHINA
Pharmacology and pharmacodynamics studies are of great importance in determining a drug's effect during drug discovery and development. A large variety of animal models has been developed to provide investigators with the ability to characterize the pharmacokinetics and pharmacodynamics of ...
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Manufactured by Creative Biolabsbased in CHINA
Pharmacokinetics (PK) dedicated to determining the mechanisms of a drug's absorption, biodistribution, when it eliminated from the body and what it becomes. It is a study of how an organism affects a drug. In vivo PK studies are critical to ensure drug candidates have appropriate PK properties that can be evaluated in preclinical ...
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Manufactured by CD Formulationbased in USA
Solubility and bioavailability issues run through drug metabolism and pharmacokinetic evaluation of candidate compounds, preclinical prescription development, and commercial formulation development. From the toxicological evaluation stage, CD Formulation has a perfect drug metabolism and pharmacokinetic support system, each experiment ...
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Manufactured by Creative Biolabsbased in CHINA
Small molecule inhibitors are a class of small molecules that interact with proteins and reduce the biological activity of target proteins. The structure of small molecule inhibitors has good spatial dispersion, and their chemical properties determine their good pharmacodinemic properties and pharmacokinetic properties. These characteristics ...
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Manufactured by Alfa Chemistrybased in USA
Lead optimization is a complex and iterative process for identifying an improved drug lead with the goal of progressing to a preclinical candidate by altering the chemical structure of a confirmed hit. A diversity of properties such as target’s specificity, selectivity, pharmacodynamics, pharmacokinetics and toxicological properties are ...
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Manufactured by ACROBiosystemsbased in USA
Anti-idiotypic antibodies are antibodies that target the variable region of another antibody to produce specific binding. These antibodies are widely used in drug development: they can be used as an important reference standard for immunogenicity analysis or can be developed to specifically detect antibody drug levels for pharmacokinetic ...
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Manufactured by Alfa Chemistrybased in USA
parameters and pharmacokinetic properties by calculating the physical and chemical indicators of one or more small molecules. We also study the drug-like properties and pharmacochemical friendliness to support your drug discovery. Learn more at ...
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Manufactured by CD Formulationbased in USA
CD Formulation researchers have conducted extensive research and development of drug delivery systems (DDS) in order to improve the pharmacokinetics and pharmacodynamics of drugs by delivering the required dose at the target site at the appropriate time and rate. Our drug delivery system development offerings include nanoparticles and ...
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based in USA
CTEH®’s pharmacology & toxicology professionals have extensive experience assessing the human toxicity of drugs and chemicals, and drug interactions and adverse reactions. CTEH® provides additional experience in pharmacokinetic analysis. Levels of drugs or chemicals in blood and/or urine are frequently key pieces of ...
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