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Mtoz Biolabs Studies And Clinical Services

7 services found

MtoZ Biolabs - PROTAC Drug Off-Target Protein Assessment Service

MtoZ Biolabs - PROTAC Drug Off-Target Protein Assessment Service

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Proteolysis targeting chimera (PROTAC) drugs offer a novel approach to disease treatment by leveraging the body's innate protein degradation pathways. In contrast to traditional small-molecule inhibitors, PROTAC drugs promote the degradation of specific proteins rather than directly inhibiting their function, thus mitigating or eliminating their role in disease progression. ...
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MtoZ Biolabs - Short-Chain Fatty Acids Analysis Service

MtoZ Biolabs - Short-Chain Fatty Acids Analysis Service

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Short chain fatty acids (SCFAs) are a subgroup of saturated aliphatic fatty acids containing 2-5 carbon atoms, with acetate (C2), propionate (C3), and butyrate (C4) being the most abundant. They are the final products of dietary fiber fermented by beneficial coliform bacteria. Humans lack enzymes capable of degrading large amounts of dietary fiber, which passes undigested through the upper ...
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MtoZ Biolabs - Biosimilar Assessment Service

MtoZ Biolabs - Biosimilar Assessment Service

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Biosimilars are biological products that are highly similar to an approved original biological drug (reference or brand drug) without any clinically meaningful differences in quality, safety, or efficacy compared to those approved. Biosimilars typically enter the market after the patent protection period of the original drug has expired, providing a more cost-effective treatment ...
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MtoZ Biolabs - Small Molecule Actives Identification and Quantification

MtoZ Biolabs - Small Molecule Actives Identification and Quantification

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Small molecule drugs, predominantly chemically synthesized drugs with molecular weight lower than 1000 Da. These drugs are characterized by their widespread use and mature theoretical foundations. Statistically, small molecule drugs comprise about 98% of commonly used medications. ...
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MtoZ Biolabs - Antibody Drug Analysis Service

MtoZ Biolabs - Antibody Drug Analysis Service

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Antibody therapies leverage human immune system antibodies to treat diseases by targeting specific proteins on pathogens or abnormal cells with exceptional precision. The development of antibody therapies has evolved from early polyclonal sera to monoclonal antibodies, and now to genetically engineered antibodies, focusing on enhancing drug safety, effectiveness, and manufacturing ...
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MtoZ Biolabs - Eukaryotic Transcriptome Sequencing Service

MtoZ Biolabs - Eukaryotic Transcriptome Sequencing Service

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Transcriptome sequencing involves sequencing the complete mRNA within cells during specific developmental stages or physiological conditions. This technique aids in studying gene expression levels and gene structure at a comprehensive level, elucidating molecular mechanisms in specific biological processes. It is widely applied in basic research, clinical ...
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MtoZ Biolabs - Applications of Single-Cell Sequencing

MtoZ Biolabs - Applications of Single-Cell Sequencing

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Humans are highly organized systems comprised of approximately 3.72×1013 cells of various types, which maintain proper organ function and normal cellular homeostasis. Despite significant and revolutionary discoveries in the field of cell biology, the heterogeneity of cells still requires further investigation. Single-cell RNA sequencing (scRNA-seq) has become the latest method for revealing the ...
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