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T Cell Services
59 services found
Manufactured by:Genekam Biotechnology AG based inDuisburg, GERMANY
There are many laboratories developing CAR T-cell therapies. Genekam has a number of kits to develop CAR T-Cell therapy e.g. isolate large number of T cells (CD4 / CD8) from blood or other source. This isolation kit will generate larger number of needed T cells ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
CRISPR/Cas9 technology has been used as a genome-editing tool for multiple cell lines, such as tumor cell line and embryonic stem cell lines. Primary T cell, as an important class of immune cells system, play an extremely important role in immunity system. It holds great potential for therapeutic ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
As the main component of the immune system, T cells protect the body from infections and tumors by a diversity of bio-functions, including recognition and presentation specific antigens, directly killing target cells, secretion cytokines, assisting or inhibiting antibody production by B cells, etc. These functional ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Activation and proliferation of γδ T cells play a significant role in diverse infectious diseases induced by bacteria, viruses, and parasites and exert their potential effector function to effectively eliminate the infection. Creative Biolabs is harnessing the unique properties of γδ T cells to develop potent and targeted ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Skin-resident γδ T cells as important components of skin immunity engage in wound healing, regulation of immune response to injury, inflammation, and re-epithelialization. They may present a new therapeutic approach to wound healing. As a leader in the research of γδ T cells, Creative Biolabs is driven to provide comprehensive γδ ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
γδ T cells are a distinct subgroup of T cells that play a pivotal role in many neurological diseases. They are suggested to be responsible for inducing or maintaining the proinflammatory environment characteristic of these diseases. With access to advanced instruments, fit-for-purpose laboratories, and professional knowledge, ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Autoimmunity is a condition in which the immune system responds to and attacks self-antigens or self healthy cells and tissues. Autoimmunity to self-antigens or a low level of autoimmunity is considered to be beneficial and important to self-defense mechanisms and immune surveillance. However, an aberrant autoimmune response that the immune system attacks and damages healthy body ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
γδ T cells are a distinct subgroup of T cells containing T cell receptors (TCRs) γ and TCR δ chains. Compared to αβ T cells, γδ T cells without MHC restriction on tumor antigen recognition have strong cytotoxic effects on tumor ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
T cells play a vital role in destroying pathogens and monitoring pathological cells. They are able to distinguish between self-antigens and non-self-antigens by surface T cell receptors (TCRs). Most human T cells express the classical TCRs, which consists of TCRα and TCRβ chains ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Creative Biolabs concentrates on promoting the understanding of gamma delta (γδ) T cell receptors breakthroughs in disease therapy. We will combine γδ T cell receptor (TCR) repertoires analysis research with other incredible projects around the world to boost novel γδ T cell development in ...
Manufactured by:Targazyme, Inc. based inCarlsbad, CALIFORNIA (USA)
TILs are part of the body’s natural response to cancer:The cells of the immune system perform immunosurveillance while circulating throughout the bodyAs part of the normal immune response, TIL migrate to the tumor site through recognition of chemokines produced by the tumor. TIL recognize tumors through tumor-specific antigens (TSAs) and can cause lysis to tumor cellsSolid tumors are ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
To accelerate the development of cancer immunotherapy, it is essential to systematically identify tumor antigens that are truly tumor-specific, patient-shared, stably expressed (i. e., cloned) and immunogenic in all malignant cells. Immunopeptidomics is a large-scale and in-depth approach capable of identifying and quantifying the presented human leukocyte antigen (HLA) immunopeptidome. ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
T cells from a healthy patient′s blood are collected and are genetically modified to express an artificial receptor consisting of the variable fragment of an antibody specific for a cell surface molecule involved in T cell signaling. CAR-T cells are then propagated in ...
Manufactured by:Immatics N.V. based inTuebingen, GERMANY
Patients eligible for clinical trials with ACTengine® product candidates have a portion of their white blood cells collected using a well-established process called leukapheresis, a procedure in which a fraction of the white blood cells of a patient is extracted from their peripheral blood. These white blood cells are transferred to a ...
Manufactured by:Immatics N.V. based inTuebingen, GERMANY
Immatics’ latest proprietary ACTengine® manufacturing processes are designed to generate cell product candidates within a short manufacturing window and deliver highly proliferative T cells, with the capability to infiltrate the patient’s tumor and function in a challenging solid tumor microenvironment. Immatics is actively ...
Manufactured by:iRepertoire, Inc. based inHuntsville, ALABAMA (USA)
When RNA is extracted for bulk repertoire sequencing, information related to the cognate pairing of BCR and TCR chains is lost. Our single cell service, iPair, is the first consumer-based service specifically designed for capturing physically paired variable regions in T cells and B ...
Manufactured by:POP Biotechnologies, Inc. (POP BIO) based inBuffalo, NEW YORK (USA)
CoPoP enables liposomes to stably bind short MHC-I epitopes upon admixture. Better delivery of epitopes and adjuvants to immune cells in draining lymph nodes. Induce higher frequency of antigen specific CD8+ T cells with > 10,000X lower peptide ...
by:Revvity Gene Delivery (formerly SIRION Biotech) based inHamburg, GERMANY
Supporting lentiviral vector development for cell therapies; Lentivirus is an efficient tool for fast, efficient, and cost-effective generation of stable homogeneous cell models for strong gene expression or gene knockdown. In gene therapy, Lentiviruses are widely used for CAR-T cell therapy ...
Manufactured by:iRepertoire, Inc. based inHuntsville, ALABAMA (USA)
Cost-effective solutions for discovering rare clonotypes. iRepertoire’s RepSeq service (formerly AMP2Seq) utilizes our patented arm-PCR technology, which uses hundreds of VDJ-specific primers in one reaction to semi-quantitatively and inclusively amplify all of the expressed V(D)Js in B or T cells from a single sample. RepSeq is our most cost-efficient ...
Manufactured by:Sanquin based inAmsterdam, NETHERLANDS
Our proprietary technology for UV-induced MHC-peptide exchange is ideally suited for high-throughput screening of peptide-binding to the MHC class I complexes. Moreover, combinatorial coding enables fast finding of relevant peptide-specific cytotoxic T ...