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Therapeutics Announces Lead Candidate Services

13 services found

Discovery Services

Discovery Services

Manufactured by:Rocket Pharmaceuticals, Inc.   based inCranbury, NEW JERSEY (USA)
Rocket’s Research and Discovery group in the Cranbury, New Jersey facility utilizes approximately 20,000 square feet of state-of-the-art laboratories for designing, optimizing and advancing candidate therapeutics to clinical stage ...
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Affinity Screen Services

Affinity Screen Services

Manufactured by:Orbit Discovery   based inOxford, UNITED KINGDOM
The Orbit Discovery Affinity Screening platform offers a proprietary technology enabling the construction of massive bead-based libraries with peptides displayed on their surface. Each bead carries a unique DNA sequence, which is translated into peptide using in vitro transcription translation (IVTT) performed in an emulsion (emIVTT). Each droplet of the emulsion acts as a micro-compartment ...
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Technological Capabilities Services

Technological Capabilities Services

by:Longeveron, Inc.   based inMiami, FLORIDA (USA)
Our lead product, Lomecel-B, consists of human allogeneic bone-marrow derived MSCs as the active ingredient. These cells undergo cultured-expansion using proprietary processes, and are then formulated, packaged and stored frozen (cryopreserved) until shortly before use. Fresh bone marrow is procured from established, licensed U.S.-based third-party tissue suppliers, which harvest the tissue from ...
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Manufacturing Services

Manufacturing Services

by:Longeveron, Inc.   based inMiami, FLORIDA (USA)
Our lead product, Lomecel-B, consists of human allogeneic bone-marrow derived MSCs as the active ingredient. These cells undergo cultured-expansion using proprietary processes, and are then formulated, packaged and stored frozen (cryopreserved) until shortly before use. Fresh bone marrow is procured from established, licensed U.S.-based third-party tissue suppliers, which harvest the tissue from ...
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Antibody Drug Conjugate Services

Antibody Drug Conjugate Services

by:Revvity Gene Delivery (formerly SIRION Biotech)   based inHamburg, GERMANY
In the discovery of oncology therapeutics, Antibody-drug conjugates (ADCs) are rapidly gaining momentum, with hundreds of candidates advancing through clinical development. Whether your priority lies in assessing the epitope binding of your construct, evaluating the cytotoxic potency of the payload, or scrutinizing the efficacy of the linker in cleaving, each facet demands meticulous ...
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Fibroblast to Myofibroblast Transition (FMT) Assay Services

Fibroblast to Myofibroblast Transition (FMT) Assay Services

Manufactured by:Newcells Biotech Limited   based inNewcastle Upon Tyne, UNITED KINGDOM
In vitro assessment of Fibroblast-to-Myofibroblast transition (FMT). Newcells offers a fast and reliable FMT assay service to evaluate the efficacy of anti-fibrotic compounds using high-content imaging. This customisable, high-throughput assay is well suited to compound screening for small molecules targeting lung fibrosis. Normal repair processes are defective in the fibrotic lung. Repetitive ...
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Clinical Trial Programs

Clinical Trial Programs

Manufactured by:Kura Oncology, Inc.   based inSan Diego, CALIFORNIA (USA)
Kura Oncology’s clinical trial programs represent the next step toward our goal of realizing the full potential of precision medicine. Our investigational trials are studying innovative therapeutic candidates with the potential to help patients with certain cancers live better, longer lives. ...
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Rapid Custom Antibody Generation for SARS-CoV-2 Assay Development

Rapid Custom Antibody Generation for SARS-CoV-2 Assay Development

Manufactured by:Bio-Rad Laboratories, Inc. (Antibodies)   based inHercules, CALIFORNIA (USA)
Reduce Lead Time for Antibody Generation: Assays supporting SARS-CoV-2 vaccine, therapeutic, and diagnostic test development must be robust, scalable, and transferable to laboratories worldwide. They need to be designed and validated rapidly, yet without compromising quality. We understand that critical antibody reagents for these vital assays must be highly specific for the chosen antigen, ...
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Bioassays for Lead Selection and Optimization

Bioassays for Lead Selection and Optimization

Manufactured by:Nexelis   based inSeattle, WASHINGTON (USA)
For R&D in Immunogenicity, Immuno-Oncology, and Cell and Gene Therapy. We have exceptional in vitro bioassay development services and support for early evaluation and screening of candidate therapeutics. Our highly experienced team will facilitate in silico immunogenicity assessment with epitope prediction to in vitro immunogenicity and immuno-functionality assays. ...
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Human Health

Human Health

Manufactured by:Dyadic International, Inc.   based inJupiter, FLORIDA (USA)
We are building an active pipeline of products for human health by applying our proprietary and patented C1 technology to develop vaccines and antibodies for infectious and other diseases. Vaccine Development: The C1 platform is ready for full commercialization opportunities in recombinant protein ...
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Drug Development Services

Drug Development Services

Manufactured by:XILIS, Inc.   based inDurham, NORTH CAROLINA (USA)
Xilis’ rapid and scalable patient-derived MicroOrganoSphere (MOS) technology platform enhances precision medicine and pharmaceutical drug discovery and development. Compared to conventional patient-derived models, MOS provides faster, higher-throughput, and greater cost savings, as well as more predictive and accurate results. MOS can be used in large-scale pharmacogenomic studies that are ...
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Radiopharmaceutical Therapy & Theranostics Services

Radiopharmaceutical Therapy & Theranostics Services

Manufactured by:Invicro, LLC   based inNeedham, MASSACHUSETTS (USA)
Radiopharmaceutical therapies represent an effective way to treat solid cancers by using tumor targeting small molecules, peptides or biologics to deliver a cytotoxic payload that induces DNA damage in tumor cells, while limiting damage to normal and healthy tissue. Streamlined development, evaluation and clinical translation of radiopharmaceuticals requires a partner that has extensive ...
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MtoZ Biolabs - Antibody-Antigen Interactions Characterization Service | HDX-MS

MtoZ Biolabs - Antibody-Antigen Interactions Characterization Service | HDX-MS

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Monoclonal antibodies (mAbs) are powerful therapeutic tools. These glycoproteins, belonging to the immunoglobulin (Ig) family, are utilized by the immune system to identify and neutralize foreign organisms or antigens. Ig’s are classified in five groups, IgA, IgD, IgE, IgG, and IgM (as α, δ, ε, γ, and μ), based on the structure of their constant regions. Among these, IgG subtypes—predominantly ...
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