Non-Invasive Prenatal Testing
From Genetic Testing
Want to make sure that your baby is growing and developing normally during pregnancy? CentoNIPT® – Safe and accurate prenatal testing – Offers you information about the health and development of your child from as early as the 10th week of pregnancy.* Non-invasive prenatal testing (NIPT) is a new method of testing for common chromosomal abnormalities that can occur in a developing baby. While rare, these chromosome abnormalities can have profound consequences to the life and health of you and your child and it is important to find out as soon as possible.
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How Does NIPT Work?
Small amounts of a baby’s DNA passes into the bloodstream of the mother during pregnancy. New technology allows us to analyse this DNA directly from the mother’s blood and screen for chromosomal abnormalities.
Previously, it was only possible to test for these abnormalities with highly invasive procedures that carried a risk to the pregnancy. Chorionic villus sampling (CVS) can be performed between weeks 10-12 and pregnancy, and amniocentesis performed between weeks 15–18 of pregnancy. These tests carry up to 1 in 150 or 1 in 100 chance of miscarriage respectively.
Initial screening with non-invasive prenatal testing can help to avoid this potentially unnecessary and invasive testing. There is no risk to mother or baby and NIPT provides the earliest testing available.
What Does CentoNIPT Screen For?
- Down syndrome (Trisomy 21), which is caused by an extra copy of chromosome 21. Mild/moderate mental retardation and risk of some birth defects (affects 1 in 1,000 live births).
- Edwards syndrome (Trisomy 18), which is caused by an extra copy of chromosome 18. Severe mental retardation and risk of multiple birth defects (affects 1 in 3,000-6,000 live births).
- Patau syndrome (Trisomy 13), which is caused by an extra copy of chromosome 13. Severe mental retardation and risk of multiple birth defects (affects 1 in every 5,000 live births).
The test can also detect abnormalities of the sex chromosomes:
- Turner syndrome (Monosomy X), which is caused by a missing X chromosome in females
- Klinefelter syndrome (XXY), which is caused by an extra X chromosome in males
- Jacobs syndrome (XYY), which is caused by an extra Y chromosome in males
- Triple X syndrome (XXX), which is caused by an extra X chromosome in females
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