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creative biogene - Oncolytic Vesicular ...

creative biogene - Oncolytic Vesicular Stomatitis Virus Service

Vesicular stomatitis virus (VSV), an enveloped, negative-strand RNA virus, belongs to the Vesiculovirus genus of the Rhabdoviridae family. VSV has the ability to infect and kill cancer cells while sparing normal cells. VSV is a rapidly replicating, potently immunogenic virus which is amenable to engineering and has been deployed as a platform to develop prophylactic and therapeutic vaccines to prevent and/or treat infectious disease and oncolytic viruses for the treatment of cancer. Recombinant attenuated VSV vectors have been shown to replicate selectively in and kill cancer cells and are not pathogenic in humans.