Pan Cancer Services
From Genomic Testing
Cancer is a complicated disease caused by genetic variation. The genetic variation may deprive cells of the normal control function, leading to immortalization and cancer. And targeted drugs work well in cancer therapy, which can kill cancer cells that carry specific genes of variation. However, patients may differ from each other regarding the in vivo genetic variation. As a result, patients vary in the susceptibility and toxic and side effects to the same anti-cancer drugs. As the more inclusive “molecular typing” is proposed, more patients are able to accept targeted therapy, where physicians can custom therapeutic regimens for cancer patients varying in genetic variation to tap as many potentially available targeted drugs as possible and enhance therapeutic efficiency of the drugs. That’s how precision medicine works. Precision medicine needs a prerequisite - precision diagnosis.
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Cancer and Precision Medicine
Cancer is a complicated disease caused by genetic variation. The genetic variation may deprive cells of the normal control function, leading to immortalization and cancer. And targeted drugs work well in cancer therapy, which can kill cancer cells that carry specific genes of variation. However, patients may differ from each other regarding the in vivo genetic variation. As a result, patients vary in the susceptibility and toxic and side effects to the same anti-cancer drugs. As the more inclusive “molecular typing” is proposed, more patients are able to accept targeted therapy, where physicians can custom therapeutic regimens for cancer patients varying in genetic variation to tap as many potentially available targeted drugs as possible and enhance therapeutic efficiency of the drugs. That’s how precision medicine works. Precision medicine needs a prerequisite - precision diagnosis.
OncoScreen Plus
Accurate and reliable full immune targeted markers test for solid tumor patients.
OncoScreen Plus was scrupulously designed, it covers 520 tumor-related genes and integrates two major international authority PANEL FoundationOne® and MSK-IMPACT® genes.
Comprehensive screening of immune molecular markers TMB, MSI, DDR pathway genes, other positive and negative prediction and hyperprogression factors, and it covers all targeted therapy related genes, comprehensively guide immune and targeted therapy.
The OncoScreen Plus • Panel size reaches 1.64Mb, and the performance parameters are consistent with the international mainstream to ensure the accurate and reliable results.
Pureplasma
Total process management solutions for solid tumor patients
Pureplasma can detect 108 genes correlated with targeting medicines in parallel for all solid tumors, meanwhile, dynamic ctDNA monitoring can be carried out to manage the whole process of patients treatment.
With the ultrahigh sequencing depth greater than 10000x, it can avoid missing important genes with low abundance mutations.
Accurate detection of mutation abundance and mutation sites, by combining with tumor heterogeneity factors, Lung Core can assist clinical selection of targeted drugs more precisely.
HRR
China’s first NGS testing solution covering all key genes in DNA repair pathways
Not only detect the BRCA gene, but also cover the DNA repair (HRR, MMR gene) cell cycle, AR, PI3K, WNT and other pathways Selected with tumorigenesis and development, targeted therapy, endocrine therapy and drug resistance related genes of ovarian cancer, prostate cancer, pancreatic cancer, breast cancer, bladder cancer, etc.
Not only detect the BRCA gene, but also cover the DNA repair (HRR, MMR gene) cell cycle, AR, PI3K, WNT and other pathways Selected with tumorigenesis and development, targeted therapy, endocrine therapy and drug resistance related genes of ovarian cancer, prostate cancer, pancreatic cancer, breast cancer, bladder cancer, etc.
Tissue test of HRR is using 1000x high-depth sequencing, blood test is 10OOOx high-depth sequencing, sensitivity and specificity beyond traditional methodology.
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