Rodent Atherosclerosis Models
Atherosclerosis is a chronic inflammatory condition that is the underlying factor of cardiovascular diseases. Both blood vessel walls and the immune system are implicated in atherogenesis. Plasma lipoproteins, genetics and the hemodynamics of the blood flow in the artery all play important roles in the development of atherosclerosis. Animal models are valuable tools for providing insights on the etiology and pathophysiology of this disease. They can be used for testing the efficacy and safety of different pharmacological therapies.
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