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Vigilant Biosciences, Inc.
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  5. Test for Oral Cancer

Test for Oral Cancer

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This year alone, oral cancer, including oral cancer, will affect the lives of hundreds of thousands of individuals and their families.

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In the US alone, oral and oropharyngeal cancer kills on average 1 person per hour, 24 hours per day.

Historically, the death rate associated with oral cancer is particularly high due to late–stage diagnosis and intervention. Currently, the vast majority of patients are detected through a visual exam and/or are symptomatic, at which point they are likely late stage. As a result, oral cancer often goes undetected to the point of metastasizing. Survival rate is only 50% due to delayed intervention with more than half of all diagnoses made at stage III and IV. However, earlier detection (stage I and II) of oral cancer yields survival rates of up to 80% to 90%.†

When caught at a late stage, the physical and psychological impact of oral cancer can be severe. Surgical removal may require reconstruction of portions of the oral cavity or facial features. There may also be therapy required to assist in speech and chewing as well as the fabrication of dental or facial prostheses.

Why is it important to test for oral cancer?
Historically, most individuals diagnosed with oral cancer were over 40 and/or tobacco users. However, the risk factors associated with oral cancers are changing and impacting a wider range of ages and backgrounds.
Anyone can get cancer, but certain factors increase your risk. Tobacco use and excessive alcohol consumption are two important risk factors associated with developing oral cancer. Another risk factor includes exposure to certain types of HPV–human papillomavirus, a common sexually transmitted virus–which is contributing to a rise in oral cancer among young people.

Elevating the Standard of Care

Currently, a visual and physical examination is the standard for an oral cancer evaluation. This is followed by a biopsy if something suspicious or abnormal is found. However, two–thirds of cases are diagnosed at stage III or stage IV with this method, resulting in a low successful cure rate. In contrast, early detection can yield an 80% to 90% cure rate.

What is needed is a simple, accurate,1 and cost–effective tool that can easily be adopted as part of the standard of care. Our goal is to empower clinicians with an aid that, along with other clinical factors, can help detect oral cancer earlier and improve potential outcomes through earlier intervention.

Addressing this need provides the opportunity for those at risk to reverse or change adverse lifestyles to lower the risk of potentially developing oral cancer. In situations where cancer started to develop, early detection testing could maximize the effectiveness of the treatment while also potentially minimizing the need for aggressive intervention that could significantly impair quality of life post–treatment.