MtoZ Biolabs -Model tumor-biology -Tumor Immunology Analysis Service
1. Requires only 25 µL of Sample, Compared to 50 µL or 100 µL of Sample for ELISA Tests
2. Suitable for Use with Serum, Plasma, Cell Culture Supernatants, and Other Body Fluids
3. Samples of Body Fluids Should be Stored at -80°C and transported on Dry Ice
During the tumor formation process, cancer cells release various cytokines and growth factors into the surroundings and reprogram many other types of cells to establish a tumor microenvironment. As a result, tumor tissues almost always contain a large number of endothelial cells, fibroblasts, and infiltrating inflammatory cells, which in turn produce various cytokines. Tumor-derived VEGF acts on endothelial cells, promoting angiogenesis and tumor growth, invasion, and metastasis. At the tumor site, monocytes differentiate into tumor-associated macrophages capable of producing growth factors, proteases, angiogenesis mediators, cytokines such as TNF-α, IL-1, and IL-6, and chemokines such as CCL2 (MCP-1), CCL5 (RANTES). Chemokines like CXCL10 (IP-10) and CXCL9 may inhibit cancer development. Additionally, many adhesion molecules, such as ICAM-1, ICAM-3, VCAM-1, and selectins, are expressed by many different types of tumor cells and are often key factors in cancer metastasis.
Turley, SJ. et al. Nat Rev Immunol. 2015.
MtoZ Biolabs uses flow cytometry to simultaneously quantify tumor-related cytokines and proteins, offering higher sensitivity and a broader detection range. The table below lists the cytokines detectable in human samples, and MtoZ Biolabs also provides detection for other species and free consultation is available!
1. Experimental Procedures
2. Raw Data (Fluorescence Emission Spectra)
3. Comprehensive Technical Report
3. Detailed Quantification of Each Indicator (Excel Spreadsheet)
MtoZ Biolabs is an integrate contract research organization (CRO) providing advanced proteomics, metabolomics, bioinformatics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. The name of MtoZ represents “mass to charge ratio” in mass spectrometry analysis, as most of our services are provided based on our well-established mass spectrometry platforms. Our services allow for the rapid and efficient development of research projects, including protein analysis, proteomics, and metabolomics programs.
MtoZ Biolabs is specialized in quantitative multiplexed proteomics and metabolomics applications through the establishment of state-of-the-art mass spectrometry platforms, coupled with high-performance liquid chromatography technology. We are committed to developing efficient, and effective tools for addressing core bioinformatics problems. With a continuing focus on quality, MtoZ Biolabs is well equipped to help you with your needs in proteomics, metabolomics, bioinformatics, and biopharmaceutical research. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample.
Email: marketing@mtoz-biolabs.com