Strand Life Sciences Pvt. Ltd.
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Variant Curation Services
Laboratories running NGS-based clinical tests are challenged with the labor of variant interpretation. To support our clinical diagnostics business, we have built up databases of curated variants across 3 different application areas:
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- Somatic Tumor Profiling: This database contains over 10,000 somatic variants curated for oncogenicity, 100 genes curated for druggability and 500 drugs curated for evidence for response in multiple cancer types
- Hereditary Cancer: This database contains over 5000 variants curated for pathogenicity across multiple inherited cancers based on ACMG guidelines
- Rare Inherited Disorders: This database contains over 10,000 variants curated for pathogenicity across multiple different mendelian disorders based on ACMG guidelines.
We work with several clinical laboratories to license and/or customize these databases based on their requirements.
Application 1. Do you want to bring your NGS somatic panel reporting in-house?
Application 2. Do you want to make NGS germline panel reporting more efficient by pre-curating variants?
Application 3. Do you want to reduce costs of variant annotation dramatically?
Application 4. Do you want to keep up to date with rapidly growing literature?