Genomically Ordered Relational Database (GORdb) Software
Proven on over two decades of population genomics, Genuity Science’s platform has a long history of solving the challenges of genomic big data. At the core of the platform is the Genomically Ordered Relational Database (GORdb) – the architecture of which was originally designed at deCODE in order to address the challenges of scalability and flexibility.
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Cohort Analytics Platform Details
GORdb
- Ingest and query next-generation sequencing (NGS) data at biobank scale. A genomically ordered architecture gives researchers the freedom to query the genome in real-time.
Phenotypes
- Unified platform for both genomic and phenotypic data. Stratify cohorts, segment cases and controls, and perform clinicogenomic analysis using longitudinal clinical attributes.
Suite of Workflows
- Integrated set of workflows for use cases ranging from carrier analysis to cohort-wide association studies. Built for reproducibility and scale on top of Nextflow and Kubernetes.
Reference Datasets
- Harmonized and updated quarterly: clinical knowledge bases, allele frequencies, disease ontologies, public association studies, gene nomenclatures, QTLs.
API
- R and Python software development kits (SDKs) easily downloadable as packages. Call the RESTful APIs of GORdb directly from RStudio and Jupyter Notebooks.
Jupyter Notebooks
- JupyterHub cluster deployed out of the box as part of the cloud instance. Enables ad hoc scripting via the API for downstream analysis and interactive visualization.
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