AlloSeq -Model Tx17 -HLA Typing Software
AlloSeq® Tx 17 is an innovative NGS HLA typing solution that uses Hybrid Capture Technology, which eliminates the inefficiencies and limitations of traditional Long-Range PCR methods. AlloSeq Tx 17 goes beyond the traditional transplant related loci to consider more transplant associated genes and helps you to identify the best genetic match.
- No long-range PCR inefficiencies-and no artifacts or crossovers
- Improved allele balance and reduced dropout rates
- Easy single tube workflow with early indexing and sample pooling
- Expanded gene content enabling the highest level of transplant matching
- Fast import speed and optimized data analysis with AlloSeq Assign® software
- Allele level resolution with low rates of ambiguity
- Maximum coverage of 17 loci including all exons for all genes
A whole genome library is prepared using bead-bound transposons. Each sample is indexed and pooled together into a single tube. Genes of interest are captured with biotinylated probes and enriched for sequencing on an illumina system. Data is analyzed using AlloSeq Assign software.
One extra pipetting step during hybridization set up allows your laboratory to capture additional content alongside AlloSeq Tx17.
- Modular Add-Ons can be used with any existing AlloSeq Tx kit
- No need for a separate library or hybridization set up
- Get more value from each single reaction with no extra hands-on time
- Expand and customize your typing menu to assist with better matching
- Choose the targets relevant to your laboratory and only pay for what you use = more flexibility