OncoPortal - Version Plus - Reporting Software
From Other Software
Clinical interpretation has been one of the most complex and time-consuming aspects of transforming genomic data into meaningful results, until now.
Software Details
As science evolves, more target genes are discovered, and comprehensive genomic profiling becomes standard of care, molecular laboratories must aggregate ever increasing amounts of information from multiple sources to interpret their genomic findings and prepare comprehensive reports.
OncoPortal™ Plus supports better and faster decision making with consistent and accurate interpretation of clinically significant biomarkers. OncoPortal Plus saves time and reduces errors that may result from manual interpretation. In tandem, our new Reporting tools enable any molecular laboratory to prepare state-of-the-art comprehensive genomic reports, while giving them the flexibility to design custom report templates to meet the unique needs of their oncologists
OncoPortal™ Plus uses molecular profiles providing a better way to review and interpret biomarkers, eliminating redundant entries, and reducing the probability of missing a biologically relevant co-occurring biomarker. Rather than considering each biomarker individually, a user can quickly assess clinical associations for molecular profiles, which consider one or multiple biomarkers, including wild type, and their compound biological effect.
All biomarker types are classified according to AMP/ASCO/CAP guidelines with tiers and evidence levels. Curated interpretative text explains the gene and variant function, and clinical associations between a molecular profile and therapeutic, diagnostic, or prognostic information. Each clinical association is supported with references to original sources including literature, guidelines, and drug labels from leading global drug agencies, bringing confidence and transparency to clinical interpretation.
After clinical interpretation, the reporting tools aggregate data from OncoPortal™ Plus and SOPHiA DDM™, enabling users to prepare push-button comprehensive reports. Users can easily configure an unlimited number of custom report templates in the Template Manager to meet medical expert preferences and comply with local reporting rules and standards.
Reports are streamlined with intuitive formatting to ensure efficient communication of the findings without information overload. Case information and an overview of key insights are all found on the first page. The overview contains the actionable biomarkers, approved therapies, and a summary of other relevant biomarkers. The report is supplemented with more detailed variant information, in the form of variant cards and interpretive text. To ensure quality and consistency, all clinical associations and interpretive text is curated by a dedicated, team of experts, never crowd-sourced.
Key Benefits
- Clinical associations, including therapeutic, diagnostic, or prognostic information support, and emerging evidence
- Transparent biomarker identification, including confidence levels
- Global clinical trial information with inclusion criteria
- AMP/ASCO/CAP classification of biomarkers, including Tier III (VUS)
- SOPHiA GENETICS knowledge base with up-to date, expertly curated content from JAX-CKB
- Rich interpretive information with references to publications, guidelines, and regulatory approvals
- Review co-occurring biomarkers, including wild type, in a more intuitive way by visualizing molecular profiles
- Easy to use filters to focus on the most relevant Molecular Profiles and Clinical Trials
- Free, unlimited, and customizable report templates
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