The Paige Prostate Suite is comprised of Paige Prostate Detect, Paige Prostate Grade & Quantify, and Paige Prostate Perineural Invasion. The AI applications available in the Paige Prostate Suite aim to assist in efficiencies of reads and reduce errors by identifying suspicious regions of interest.
Paige Prostate Detect
Paige Prostate Detect assists pathologists in the detection of foci that are suspicious for cancer during the review of scanned whole slide images (WSI) from prostate needle biopsies prepared from hematoxylin & eosin (H&E) stained formalin fixed paraffin embedded (FFPE) tissue. Paige Prostate Detect detects a region of interest with the highest likelihood of harboring cancer for further review by a pathologist.
In one high profile study, Paige Prostate Detect had close to 100% sensitivity and 100% negative predictive value at patient level with reduced time to diagnosis by 65%
In a study submitted to the FDA, and leading to the first FDA approval of a pathology AI application, Paige Prostate Detect was shown to significantly improve the sensitivity and specificity of the diagnosis of prostate cancer with an average 70% reduction in false negative diagnoses.
Paige Prostate Grade & Quantify
Paige’s proprietary tissue map highlights areas suspicious for cancer and categorizes them by Gleason pattern to assist pathologists in evaluating values for overall tumor percentage and tumor length.
Percentages and locations of Gleason patterns in a slide are conveniently displayed with just a click, for easy and efficient visualization. This application aims to reduce inter- and intra-observer variability, by helping pathologists standardize their approach to grading of prostate cancer.
Paige Prostate Perineural Invasion (PNI)
The Paige Prostate Perineural Invasion (PNI) application aids pathologists to identify the presence of suspicious foci around nerve fibers within the prostate for a quick detection of PNI in prostate biopsies.
When combined with detection, Gleason grade and tumor percentage, PNI detection can provide pathologists comprehensive insights assisting is a more confident diagnosis.