Allografts Applications
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Biomaterial product solutions for tendon repair areas
Allograft/xenograft tissue is extensively used as a protector and adhesion resistant membrane in tendon repair (e.g., rotator cuff, Achilles, ACL, ...
By Viscus Biologics LLC based in Cleveland, OHIO (USA).
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Calcium phosphate bioceramics solutions for trauma sector
Trauma can result in extensive destruction to bone and the potential loss of bone material. Reconstruction may require instrumentation to stabilize the damaged site and some form of scaffold material to facilitate bone healing across large gaps. Allograft bone chips from bone fragments caused by the trauma are the best scaffold source but if they are not sufficient an additional scaffold material may be needed. Synthetic calcium phosphates can serve as supplementary scaffold/graft ...
By CaP Biomaterials, LLC based in East Troy, WISCONSIN (USA).
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i-FACTOR Bone Graft Facilitates
i-FACTOR Bone Graft facilitates the ingrowth of bone by promoting the migration of mesenchymal stem cells and other progenitor cells from surrounding ...
By Cerapedics, Inc. based in Westminster, COLORADO (USA).
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Calcium phosphate bioceramics solutions for spine industry
Spinal fusion is the largest user of bone grafting materials. The goal is to generate bone where no bone naturally exists in order to bring about fusion across two or more vertebra. Traditionally iliac crest bone chips have been the main source of a scaffold material to facilitate the necessary bone growth. Such bone chips work very well for fusion but co-morbidity at the iliac crest harvest site can result in the patient experiencing as much pain from the harvest site as from their original spinal complaint. ...
By CaP Biomaterials, LLC based in East Troy, WISCONSIN (USA).
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IDE Study - i-FACTOR Superior to Autograft in Overall Success
The pinnacle of scientific evidence is the Level I study. i-FACTOR Bone Graft is one of a small group of bone grafting technologies that is supported by Level I evidence. i-FACTOR Bone Graft was evaluated in a 319-patient, prospective, randomized, controlled, multi-center clinical trial assessing its safety and efficacy compared to standard-of-care (autograft). Patients underwent anterior cervical discectomy and fusion (ACDF) and received either i-FACTOR Bone Graft or local autograft in a cortical allograft ring ...
By Cerapedics, Inc. based in Westminster, COLORADO (USA).
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Biomaterial product solutions for ophthalmic areas
Demineralized bone matrix is essentially a collagen matrix. Collagen, allograft, or xenograft tissue is used extensively in orthopaedic procedures as either a filler material, or as a barrier or biologic for improving healing. ...
By Viscus Biologics LLC based in Cleveland, OHIO (USA).
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Calcium phosphate bioceramics solutions for synthetic bone applications
Calcium phosphate bioceramics such as HA or TCP or biphasic HA/TCP are very similar in composition to the main mineral portion of bone. These ceramics have demonstrated excellent biocompatibility. In porous forms, the structure mimics the structure of bone. Interconnected pores of sufficient size have been shown to provide a highly biocompatible matrix for osteoconduction. The use of these synthetic graft materials avoids some of the concerns with allografts (human bone source) and xenograft’s (animal bone ...
By CaP Biomaterials, LLC based in East Troy, WISCONSIN (USA).
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Biomaterial product solutions for wound repair areas
Collagen or allograft/xenograft tissue makes up the majority of the advanced wound dressing market. The collagen and remnant growth factors in the tissue contribute to improved healing by attracting additional wound healing cells such as fibroblasts into the area. The presence of collagen also reduces excess proteinases and gelatinases that unbalance the wound microenvironment and breakdown the rebuilding wound in chronic ...
By Viscus Biologics LLC based in Cleveland, OHIO (USA).
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IVANOS study - Level 1 Study: i-FACTOR vs. Bone Bank Allograft in a Challenging Fusion Environment
Due to poor bone stock in the elderly, a non-instrumented fusion is commonly performed in Scandinavia when instability is present. Allograft bone is often used as graft extender with consequent low fusion rates. The aim of this study was to evaluate the performance of i-FACTOR against Bone Bank ...
By Cerapedics, Inc. based in Westminster, COLORADO (USA).
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