cell-line-development Videos
3 videos found
Enzymes can be challenging to express and scale up to become biologic therapies. In order to develop their optimized tissue plasmigen activator (tPA) to treat patients with hemorrhagic stroke, Op2Lysis came to Catalent Biologics to develop a cell line expressing their optimized tPA enzyme. By leveraging GPEx® ...
Jan. 31, 2023
Intensified process formats promise improved cost efficiency in biotherapeutics production by lowering cost of goods and increasing plant flexibility. CHO clones from traditional cell line development differ in responsiveness to process intensification and sometimes fail altogether. Therefore, tailored and time-efficient approaches are key to ...
Aug. 13, 2019
