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Drug Delivery Product Applications For The Served Medical Health Care Industry
13 applications found
Collagen coatings may be used as a vehicle for drug ...
ByViscus Biologics LLC based in Cleveland, OHIO (USA)
The defense mechanisms observed in the eye (epithelium, tear flow and blinking reflex) hamper the drug penetration into deeper layers of the eye. The use of modified liposomes with mucoadhesive polymers and a specific lipid formula helped in overcoming these surface obstacles and reaching target areas as the conjunctival ...
ByNanovex Biotechnologies based in Llanera, SPAIN
Drug delivery in the retina is normally performed through intravitreal injection but it is only suitable for compounds fitting a list of criteria like long half-lives. ...
ByNanovex Biotechnologies based in Llanera, SPAIN
Glaukos is developing multiple micro-invasive, bioerodible, sustained-release drug delivery platforms designed to be used in the treatment of various retinal disease, including age-related macular degeneration (AMD) and diabetic macular ...
ByGlaukos Corporation based in San Clemente, CALIFORNIA (USA)
The delivery of therapeutical compounds such as RNA drugs into the brain presents the challenges of RNA preservation and the crossing of the blood brain barrier. ...
ByNanovex Biotechnologies based in Llanera, SPAIN
A transdermal patch is a method of drug delivery through the skin into the bloodstream. The patch contains a drug which absorbs into your skin when attached to you and it releases a consistent ...
ByEdinburgh Instruments - TECHCOMP Group based in , UNITED KINGDOM
The trespassing of the blood brain barrier is a challenge for the treatment of central nervous diseases such as Alzheimer, Parkinson, stroke, or cancer (glioma). The endothelium shows tight junctions and specialized transporters which limits the bioavailability of drugs in the central nervous ...
ByNanovex Biotechnologies based in Llanera, SPAIN
Kirkstall’s Quasi Vivo® system aims to establish and optimise a human in vitro 3D Blood Brain Barrier (BBB) in an effort to identify important mechanistic pathways for successful biomarker analysis, drug delivery and toxicity ...
ByKirkstall Ltd. based in York, UNITED KINGDOM
In many therapeutic areas, current treatments involve significant side effects. Combining drug compounds with affinity agents that target specific cell surface receptors can dramatically reduce off-target effects and improve treatment effectiveness. In several studies, aptamer-mediated drug delivery has reduced toxicity and improved drug performance. ...
ByBase Pair Biotechnologies, Inc. based in Pearland, TEXAS (USA)
However, approximately 30% of drugs fail during human clinical trials due to adverse reactions despite promising preclinical study results, and another 60% fail due to lack of efficacy. As companies broaden the modality toolbox with novel drug delivery mechanisms, clinical translation becomes even more challenging. Put simply, current models do not offer the predictive value required to confidently transition drug candidates to the ...
ByEmulate based in Boston, MASSACHUSETTS (USA)
The growing adoption of focused ultrasound to treat tissue non-invasively with thermal or mechanical energy requires robust measurements to ensure safety and ...
ByOnda Corporation based in Sunnyvale, CALIFORNIA (USA)
Aptamers are short strands of DNA or RNA with unique secondary and tertiary structures that enable highly selective binding to various types of targets. While aptamers are similar to antibodies in their ability to specifically bind with high affinity, there are some key differences between antibodies and aptamers which have prompted an increase in aptamer development projects. Several hot areas for aptamers, along with specific aptamer advantages, are outlined below. ...
ByBase Pair Biotechnologies, Inc. based in Pearland, TEXAS (USA)
In modern medicine there is a constant demand to collect data about patients’ physical, physiological and behavior, monitor medical instruments inside hospitals to reduce multiple systems or shortage, monitor hospital staff’s hygiene with a dedicated bracelet and many other applications that requires monitoring and data ...
BySol Chip Ltd. based in Haifa, ISRAEL