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Preclinical Testing Product Applications In Europe
5 applications found
Rodent mammary carcinoma, mice lung cancer, glioma and pancreatic cancer are just some targeted diseases in preclinical testing using exosome delivery technology. Examples of peptides and targeting ligands for exosome decoration are integrin specific RGD for mice mammary tumor or GE11 synthetic peptide for EGFR+ breast ...
ByNanovex Biotechnologies based in Llanera, SPAIN
The development of highly cytotoxic drugs is needed for the success of the treatment in tumor cells. Paradoxically, the high toxicity limits its efficacy and application in vivo, causing damage to non-target organs and severe secondary effects. The use of directed liposomes has allowed the advance of many cancer drugs to preclinical and clinical trials, reducing side effects, and increasing their therapeutic index at the same time. More than 15 cancer liposomed drugs are currently clinically ...
ByNanovex Biotechnologies based in Llanera, SPAIN
Anesthesiologist Dr. Egbert Mik, building on his invention made together with Dr. Michiel Sinaasappel, developed the protoporphyrin IX triplet state lifetime technique (PpIX-TSLT). It is the first practical way to clinically measure oxygen availability and consumption where oxygen is needed: in the tissue cells rather than in the blood. It uses the oxygen dependent duration of the 'glow-in-the-dark' of the precursor to heme. This protoporphyrin IX is metabolized in epidermal mitochondria after local priming with ...
ByPhotonics Healthcare BV based in Utrecht, NETHERLANDS
Thermal Management: Pyroid HT pyrolytic graphite thermal spreaders and thermal vias are a powerful new material solution in the battle against thermal heat in state-of-the-art electronic circuits and devices. HT material matches the heat spreading capability of CVD diamond at 1700 W/mK but at substantially better economics. ...
ByCETCO based in New York, NEW YORK (USA)
Iconeus is leveraging its expertise in preclinical research to develop innovative clinical applications using its Iconeus One CR functional ultrasound system. This system is instrumental for transcranial ultrasound localization microscopy (ULM), allowing for the imaging of the brain's microvasculature at a microscopic resolution, which is particularly beneficial for diagnosing and monitoring stroke and aneurysm. The system's current projects, in collaboration with entities like Geneva University and Physics for ...
ByIconeus based in Paris, FRANCE