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Therapeutic Antibody Product Applications In Europe
6 applications found
Monoclonal antibodies (mAbs) are used to treat patients in a variety of conditions such as infectious disease, cancer, and autoimmunity. Discovery of therapeutic antibodies is a laborious process, that depends on high-throughput screening of antibody candidates to determine antigen specificity. Immune repertoire analysis provides accurate, sensitive, and rapid detection of antibody sequences in panning rounds or exposured animal ...
ByEnpicom B.V. based in s-Hertogenbosch, NETHERLANDS
Determining adverse immune responses to monoclonal ...
ByAlcyomics Ltd. based in Newcastle Upon Tyne, UNITED KINGDOM
No single preventive health intervention is more cost-effective than immunization. Immune repertoire analysis has taken a predominant role in the development of vaccination strategies against infectious disease and has enabled characterization of the immune response against pathogens at high ...
ByEnpicom B.V. based in s-Hertogenbosch, NETHERLANDS
Comprehensive antibody reactivity profiling: validate specificity, identify cross-reactions. The issue of antibody cross-reactivity is one that has often been often overlooked or sidelined in the past, with typical antibody QC involving evidence of binding to the intended target, while neglecting potential cross-reactivity. In recent years, however, many examples have come to light where poor validation of antibodies has led to misleading or erroneous conclusions for assays in which they are used as reagents, due ...
ByCambridge Protein Arrays Ltd. (CPAP) based in Cambridge, UNITED KINGDOM
The production of large quantities with the resulting complex requirements calls for automated process concepts. To achieve this, the machines for the essential process steps of washing, sterilizing, filling and closing are combined into one line. This creates a completely customer-centric line concept based on existing and proven technology. Automation of the filling process from washing to closing or even external cleaning leads to essential process reliability, with high transport capacities going hand in hand ...
ByRota Verpackungstechnik GmbH & Co.KG based in Wehr, GERMANY
The antibody drug discovery process differs from the traditional drug discovery of small molecules as it requires the development of hybridomas and the engineering of antibodies to recognize a specific target protein. The production of recombinant antibodies in cancer treatment as well as the development of neutralizing antibodies for infectious diseases, has allowed antibody discovery platforms to interrogate the immune repertoire and develop novel antibody libraries using flow cytometry analysis and cell ...
ByNanoCellect Biomedical, Inc. based in San Diego, CALIFORNIA (USA)