Elevated Preoperative Galectin-3 Is Associated With Acute Kidney Injury After Cardiac Surgery

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1. Preoperative serum Gal-3 was measured in 1498 patients who underwent coronary artery bypass graft surgery and/or valve.
2. Patients in the highest third of Gal-3 levels had 2.95-greater odds of developing KDIGO Stage 2 or 3 (p < 0.001) and 1.71-increased odds of developing KDIGO Stage 1 (p = 0.001), compared to the lowest third.
3. Elevated preoperative Gal-3 levels significantly improve predictive ability over existing clinical models for postoperative AKI and to identify patients at the highest risk of developing AKI and AKI severity after cardiac surgery